{"title":"Biochemistry","description":null,"products":[{"product_id":"human-stem-cell-manual-a-laboratory-guide-1","title":"Human Stem Cell Manual: A Laboratory Guide","description":"Stem cells are self-replicating and undifferentiated, meaning their function is not yet cell, tissue, or organ-specific. Due to the unique nature of these cells, research into their biology and function holds great promise for therapeutic applications through replacement or repair of diseased and damaged cells. This reader-friendly manual provides a practical \"hands on\" guide to the culture of human embryonic and somatic stem cells. By presenting methods for embryonic and adult lines side-by-side, the authors lay out an elegant and unique path to understanding the science of stem cell practice. The authors begin with a broad-based introduction to the field, and also review legal and regulatory issues and patents. Each experimental strategy is presented with an historical introduction, detailed method, discussion of alternative methods, and common pitfalls. This lab guide for researchers also serves as a textbook for undergraduate and graduate students in laboratory courses.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507142455393,"sku":"9780123704658","price":36.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_3d9aa388-eb0e-4a99-9471-7ac3ac47db84.jpg?v=1778628992"},{"product_id":"bioengineering-and-molecular-biology-of-plant-pathways-1","title":"Bioengineering and Molecular Biology of Plant Pathways","description":"The increased knowledge about the structure of genomes in a number of species, about the complexity of transcriptomes, and the rapid growth in knowledge about mutant phenotypes have set off the large scale use of transgenes to answer basic biological questions, and to generate new crops and novel products.  This volume includes twelve chapters, which to variable degrees describe the use of transgenic plants to explore possibilities and approaches for the modification of plant metabolism, adaptation or development.  The interests of the authors range from tool development, to basic biochemical know-how about the engineering of enzymes, to exploring avenues for the modification of complex multigenic pathways, and include several examples for the engineering of specific pathways in different organs and developmental stages.\u003cbr\u003e\u003cbr\u003e* Prologue by Paul K. Stumpf and Eric E. Conn\u003cbr\u003e* Incorporates new concepts and insights in plant biochemistry and biology\u003cbr\u003e* Provides a conceptual framework regarding the challenges faced in engineering pathways\u003cbr\u003e* Discusses potential in engineering of metabolic end-products that are of vast economical importance, including genetic engineering of cellulose, seed storage proteins, and edible and industrial oils","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507902345313,"sku":"9780080449722","price":72.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_30ecca27-48e0-4dcc-b984-13e7c279312d.jpg?v=1778629948"},{"product_id":"advances-in-clinical-chemistry-1","title":"Advances in Clinical Chemistry","description":"For more than thirty years, this serial has broadened the technical scope and expanded the scientific base of clinical chemistry. These volumes clarify the areas of molecular biology and informatics and the monitoring of physiological parameters in critical situations as they pertain to clinical chemistry. Each volume of Advances in Clinical Chemistry contains an index, and each chapter includes references.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507909685345,"sku":"9780120103362","price":76.0,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_5bae6e3e-9b7e-462a-b5c7-43617c6e72c6.jpg?v=1778630052"},{"product_id":"advances-in-catalysis-1","title":"Advances in Catalysis","description":"Since 1948, this series has filled the gap between the papers that report on and the textbooks that teach in the diverse areas of catalysis research. The editors of and contributors to \u003cb\u003eAdvances in Catalysis\u003c\/b\u003e are dedicated to recording progress in this area. Each volume of \u003cb\u003eAdvances in Catalysis\u003c\/b\u003e contains articles covering a subject of broad interest.\u003cbr\u003e\u003cbr\u003eAdvances in Catalysis 44 reflects the expanding impact of experimental surface characterization on the understanding of catalysis. The catalysts emphasized here are representative of the complexity of today's technology; examples include catalysts for hydrocarbon re-forming, automobile exhaust conversion, and hydroprocessing to make clean-burning fossil fuels. \u003cbr\u003e\u003cbr\u003eThis volume contains three obituaries recognizing the major contributions of Dr. Werner O. Hagg, Dr. Charles Kemball, and Dr. John Turkevich.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507910471777,"sku":"9780120078448","price":92.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_0335fc0a-afce-459d-98ee-d79344d3431b.jpg?v=1778630070"},{"product_id":"advances-in-clinical-chemistry-3","title":"Advances in Clinical Chemistry","description":"This volume, edited for the last time by H.E. Spiegel, continues the objective of expanding the intellectual horizon of clinical chemistry. The fields of analytical, anatomical, sub-cellular and molecular sciences are all represented in this volume.\u003cbr\u003e\u003cbr\u003e* Detailed reviews by practicing scientists\u003cbr\u003e* Covers a broad range of clinical chemistry on a theoretical and practical basis\u003cbr\u003e* Includes easy to read chapters combining science and perspectives in a changing scientific landscape","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507914502241,"sku":"9780120103379","price":76.0,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_d613d3c6-2dc3-44e4-bdbe-f02c79f53f71.jpg?v=1778630119"},{"product_id":"advances-in-heterocyclic-chemistry-2","title":"Advances in Heterocyclic Chemistry","description":"Established in 1960, \u003cb\u003eAdvances in Heterocyclic Chemistry\u003c\/b\u003e is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507921645665,"sku":"9780120207817","price":92.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_fa68e71e-5ec3-4beb-80bf-85ea1eeb6b0f.jpg?v=1778630225"},{"product_id":"advances-in-heterocyclic-chemistry-4","title":"Advances in Heterocyclic Chemistry","description":"Established in 1960, \u003cb\u003eAdvances in Heterocyclic Chemistry\u003c\/b\u003e is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507921973345,"sku":"9780120207824","price":92.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_66cce4bf-7824-4790-8e1b-cbb347d660ec.jpg?v=1778630229"},{"product_id":"advances-in-heterocyclic-chemistry-7","title":"Advances in Heterocyclic Chemistry","description":"Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area—one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003eComprehensive reviews of topics in heterocyclic chemistry.\u003cbr\u003e\u003cbr\u003eSubject of importance to organic chemists in academia and industry, to biologists and biochemists and all scientists in related scientific areas.\u003cbr\u003e\u003cbr\u003eAuthors are established authorities in their subjects.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507922104417,"sku":"9780120207855","price":92.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_c3862085-bb3a-4281-a587-d0d17ea5d19e.jpg?v=1778630235"},{"product_id":"advances-in-insect-physiology-1","title":"Advances in Insect Physiology","description":"\u003cb\u003eAdvances in Insect Physiology\u003c\/b\u003e is committed to publishing eclectic volumes containing comprehensive and in-depth reviews on all aspects of insect physiology. First published in 1963, it is an essential reference source for invertebrate physiologists and neurobiologists, entomologists, zoologists, and insect biochemists.\u003cbr\u003eIn 1999, the Institute for Scientific Information released figures showing that \u003cb\u003eAdvances in Insect Physiology\u003c\/b\u003e has an Impact Factor of 4.5, placing it second in the highly competitive category of Entomology.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* This volume includes five reviews on the following topics:\u003cbr\u003e* The Drosophila melanogaster Malpighian tubule\u003cbr\u003e* Plasticity in the insect nervous system\u003cbr\u003e* Neutral amino acid absorption in the midgut of lepidopteran larvae \u003cbr\u003e* The unpaired median neurons of insects\u003cbr\u003e* FMRFamide related peptides: a multifunctional family of structurally related neuropeptides in insects","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507924398177,"sku":"9780120242283","price":66.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_16c1f2ef-9fed-41f0-a737-7f25a23b4b61.jpg?v=1778630269"},{"product_id":"evolutionary-approaches-to-protein-design-1","title":"Evolutionary Approaches to Protein Design","description":"This is the first high-quality, comprehensive overview of the field of evolutionary protein design. Topics include new protein design strategies, the structures of laboratory-evolved proteins, the evolution of non-natural enzyme functions, and the theory of laboratory evolution.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507930624097,"sku":"9780120342556","price":68.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_8e590a18-0c52-4435-b417-8fb49825c663.jpg?v=1778630376"},{"product_id":"drug-discovery-and-design","title":"Drug Discovery and Design","description":"Strategies to reduce medical uncertainty and build evidence have become critical to the advancement of medical knowledge and modern medical practice. As new techniques and strategies have arisen, so has the need for a current reference work. \u003cb\u003eDrug Discovery and Design\u003c\/b\u003e examines the latest research in the development of these new strategies. Some of the topics covered include angiotensin converting enzyme inhibitors, HIV protease inhibitors, PPAR agonists for diabetes, and glucan synthase antifungal agents.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507937308769,"sku":"9780120342563","price":68.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_78e33779-044b-4777-9c72-dfdaf498b5a8.jpg?v=1778630477"},{"product_id":"prion-proteins-1","title":"Prion Proteins","description":"\u003cb\u003ePrion Proteins\u003c\/b\u003e is \"issue-oriented\" and edited by a well-known authority in the field. Topics covered include structure, diversity, and energetics as well as the diseases associated with prion proteins.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507937669217,"sku":"9780120342570","price":68.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_9bb38c99-eb8f-43cb-8138-1068c974d96c.jpg?v=1778630482"},{"product_id":"membrane-proteins-1","title":"Membrane Proteins","description":"This volume covers 2 major topics: Foundations and Membrane Protein Structures.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* Foundations\u003cbr\u003e* Bioenergetic Processes\u003cbr\u003e* Channels and Receptors","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507937964129,"sku":"9780120342631","price":64.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_e1b4db02-913f-43e6-afa8-45e742052013.jpg?v=1778630486"},{"product_id":"sphingolipid-metabolism-and-cell-signaling-part-a-1","title":"Sphingolipid Metabolism and Cell Signaling, Part A","description":"Sphingolipids are found in all eukaryotic and in some prokaryotic organisms and provide structure for cell membranes, lipoproteins, and other biological materials as well as participate in the regulation of cell growth, differentiation, and diverse cell functions, including cell-cell communication, cell-substratum interactions, and intracellular signal transduction. This volume presents methods used in studying enzymes of sphingolipid biosynthesis and turnover, including inhibitors of some of these enzymes, genetic approaches, and organic and enzymatic syntheses of sphingolipids and analogs. Its companion \u003cb\u003eVolume 312\u003c\/b\u003e will contain information on analyzing sphingolipids, sphingolipid transport and trafficking, and sphingolipid-protein interactions and cellular targets.\u003cbr\u003eThe critically acclaimed laboratory standard for more than forty years, \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507964964961,"sku":"9780121822125","price":74.0,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_061a4d90-62a5-4105-8ebf-6e1abecc6a5c.jpg?v=1778630869"},{"product_id":"peptide-lipid-interactions-1","title":"Peptide-Lipid Interactions","description":"This volume contains a comprehensive overview of peptide-lipid interactions by leading researchers. The first part covers theoretical concepts, experimental considerations, and thermodynamics. The second part presents new results obtained through site-directed EPR, electron microscopy, NMR, isothermal calorimetry, and fluorescence quenching. The final part covers problems of biological interest, including signal transduction, membrane transport, fusion, and adhesion.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* world-renowned experts\u003cbr\u003e* state-of-the-art experimental methods\u003cbr\u003e* monolayers, bilayers, biological membranes \u003cbr\u003e* theoretical aspects and computer simulations\u003cbr\u003e* rafts\u003cbr\u003e* synaptic transmission\u003cbr\u003e* membrane fusion\u003cbr\u003e* signal transduction","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507965456481,"sku":"9780121533526","price":79.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_e9266d2a-d117-486a-bc83-b4451377cfa2.jpg?v=1778630879"},{"product_id":"antisense-technology-part-a-general-methods-methods-of-delivery-and-rna-studies-1","title":"Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies","description":"Antisense technology is the ability to manipulate gene expression within mammalian cells providing powerful experimental approaches for the study of gene function and gene regulation. For example, methods that inhibit gene expression permit studies which probe the normal function of a specific product within a cell. Such methodology can be used in many disciplines such as pharmacology, oncology, genetics, cell biology, developmental biology, molecular biology, biochemistry, and neurosciences. This volume will be a truly important tool in biomedical-oriented research.\u003cbr\u003eThe critically acclaimed laboratory standard for more than forty years, \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507967619169,"sku":"9780121822149","price":74.0,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_d4a3875a-eb32-4dd6-81e0-02f8ee86de9e.jpg?v=1778630912"},{"product_id":"vertebrae-phototransduction-and-the-visual-cycle-part-b-1","title":"Vertebrae Phototransduction and the Visual Cycle, Part B","description":"Major topics covered include photoreceptor proteins, phototransduction calcium-binding proteins and calcium measurement in photoreceptor cells, enzymes of the visual cycle, posttranslational and chemical modifications, analysis of animal models of retinal diseases. Inherited retinal disease; from the defective gene to its function and repair. This volume and its companion Volume 315 include newly developed methods to study vertebrate phototransduction and the visual cycle.\u003cbr\u003eThe critically acclaimed laboratory standard for more than forty years, \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507968045153,"sku":"9780121822170","price":77.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_ca3f843f-9f8d-4849-931d-1afc67daab53.jpg?v=1778630917"},{"product_id":"rna-ligand-interactions-part-b-molecular-biology-methods-molecular-biology-methods-1","title":"RNA-Ligand Interactions, Part B: Molecular Biology Methods: Molecular Biology Methods","description":"\u003cb\u003eRNA-Ligand Interactions, Part B\u003c\/b\u003e focuses on molecular biology methods. Major topics covered include: solution probe methods, tethered-probe methodologies, \u003ci\u003ein vitro\u003c\/i\u003e affinity selection methodologies, genetic methodologies for detecting RNA-protein interactions, protein engineering methodologies useful for RNA-protein interaction studies, and cell biology methods.\u003cbr\u003e\u003cb\u003eRNA-Ligand Interactions, Part A\u003c\/b\u003e, its companion, \u003cb\u003eVOLUME 317\u003c\/b\u003e focuses on structural biology methods.\u003cbr\u003eThe critically acclaimed laboratory standard for more than forty years, \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507968438369,"sku":"9780121822194","price":77.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_7c0681f3-0c4b-4042-a7a2-2c9eb04222bd.jpg?v=1778630923"},{"product_id":"singlet-oxygen-uv-a-and-ozone-1","title":"Singlet Oxygen, UV-A and Ozone","description":"Recent advances in understanding the biological role of singlet oxygen in the pathways of cellular responses to ultraviolet-A radiation: its key position in photodynamical effects, and its generation by photochemical (dark) reactions, e.g. by cells of the immune system such as eosinophils and macrophages, are the focus of this volume. The new methods and techniques responsible for the rapid progress in this area are presented. \u003cbr\u003e\u003cbr\u003eThe critically acclaimed laboratory standard for more than forty years, \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507968798817,"sku":"9780121822200","price":77.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_70ea6569-c664-4ecb-b54d-70a0d5123ba4.jpg?v=1778630932"},{"product_id":"apoptosis-1","title":"Apoptosis","description":"\u003cb\u003eVolume 322\u003c\/b\u003e of \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is dedicated to apoptosis. Major topics covered include measuring apoptosis and apoptosis-induced endonucleases, measuring apoptosis in lower organisms, proteases involved in apoptosis and their inhibitors, cell free systems for monitoring steps in apoptosis pathways, mitochondria and apoptosis, bCl-2 family proteins, and studying receptors and signal transduction events implicated in cell survival and cell death.\u003cbr\u003eThe critically acclaimed laboratory standard for more than forty years, \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507969126497,"sku":"9780121822231","price":77.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_1ebc9aae-3451-47ce-a20b-c0d698a81c9b.jpg?v=1778630937"},{"product_id":"branched-chain-amino-acids-part-b-1","title":"Branched-Chain Amino Acids, Part B","description":"\u003cb\u003eVolume 324\u003c\/b\u003e of \u003cb\u003eMethods in Enzymology\u003c\/b\u003e supplements \u003cb\u003eVolume 166\u003c\/b\u003e. It includes genetic information (cloning, gene expression) and information on human genetic diseases not available when \u003cb\u003eVolume 166\u003c\/b\u003e was published.\u003cbr\u003e\u003cb\u003eGeneral Description of the Series:\u003c\/b\u003e\u003cbr\u003eThe critically acclaimed laboratory standard for more than forty years, \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* Preparation of substrates and assay of enzymes\u003cbr\u003e* Cloning, expression, and purification of enzymes\u003cbr\u003e* Detection and consequences of genetic defects\u003cbr\u003e* Regulation and expression of enzymes","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507969257569,"sku":"9780121822255","price":77.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_aa44876d-d166-4e39-aac2-3e9a1fbe97f9.jpg?v=1778630943"},{"product_id":"regulators-and-effectors-of-small-gtpases-part-d-rho-family-rho-family-1","title":"Regulators and Effectors of Small GTPases, Part D: Rho Family: Rho Family","description":"This volume and its companions (\u003cb\u003eVolumes 255, 256, 257\u003c\/b\u003e, and the forthcoming \u003cb\u003e329\u003c\/b\u003e) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level.\u003cbr\u003eThe critically acclaimed laboratory standard for more than forty years, \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507971387489,"sku":"9780121822262","price":77.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_7b48e0f7-3623-4b27-a95a-e9b3389bfb7a.jpg?v=1778630957"},{"product_id":"applications-of-chimeric-genes-and-hybrid-proteins-part-b-cell-biology-and-physiology-cell-biology-and-physiology-1","title":"Applications of Chimeric Genes and Hybrid Proteins, Part B: Cell Biology and Physiology: Cell Biology and Physiology","description":"The critically acclaimed laboratory standard for more than forty years, \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507972862049,"sku":"9780121822286","price":77.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_615a08a6-866d-40bb-85dc-166a57438373.jpg?v=1778630963"},{"product_id":"applications-of-chimeric-genes-and-hybrid-proteins-part-c-protein-protein-interactions-and-genomics-protein-protein-interactions-and-genomics-1","title":"Applications of Chimeric Genes and Hybrid Proteins, Part C: Protein-Protein Interactions and Genomics: Protein-Protein Interactions and Genomics","description":"The critically acclaimed laboratory standard for more than forty years, \u003cb\u003eMethods in Enzymology\u003c\/b\u003e is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44507973582945,"sku":"9780121822293","price":77.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_9e712ae9-7375-4f40-a5ea-1b364eedd481.jpg?v=1778630967"},{"product_id":"alkaloids-chemical-and-biological-perspectives-volume-10-chemical-and-biological-perspectives-volume-11","title":"Alkaloids: Chemical and Biological Perspectives, Volume 10: Chemical and Biological Perspectives, Volume 10","description":"Volume 10 of this series presents four timely reviews. Chapter 1 provides a fascinating account of the history of alkaloid discovery in Australia beginning with the isolation of the first alkaloid from an Australian plant, the Tasmanian sassafras \u003ci\u003e(Atherosperma moschatum),\u003c\/i\u003e by Zeyer in 1861. Also included is a comprehensive survey of alkaloid-bearing plants, and a section dealing with detection, estimation, extraction, and work-up procedures for alkaloids.\u003cp\u003eChapter 2 provides a comprehensive update to the chapter on \"Pyridine and Piperidine Alkaloids\" which appeared in volume 3 of this series. The focus of this chapter is on new alkaloids isolated, biosynthesis, and biological properties.\u003c\/p\u003e\u003cp\u003eChapter 3 looks at \"3-Alkylpiperidine Alkaloids Isolated from Marine Sponges in the Order Haplosclerida\". Studies over the past thirty years have shown that sponges are a rich source of alkaloids. Many of these sponge alkaloids are related to each other by the presence of a 3-alkylpiperidine moiety in their structures and it happens that the sponges that have been reported to contain 3-alkylpiperidine alkaloids are all in the order Haplosclerida.\u003c\/p\u003e\u003cp\u003eChapter 4 reviews \u0026amp;bgr;-carboline and isoquinoline alkaloids which are pharmacologically some of the most significant marine natural products. This chapter treats the isolation, structure elucidation, synthesis, biosynthesis, and pharmacological activity of these alkaloids.\u003c\/p\u003e","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508009168993,"sku":"9780080427911","price":89.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_7a8b0e1b-d3f6-44b4-9f7c-472c05945954.jpg?v=1778631106"},{"product_id":"development-and-validation-of-analytical-methods-1","title":"Development and Validation of Analytical Methods","description":"The need to validate an analytical or bioanalytical method is encountered by analysts in the pharmaceutical industry on an almost daily basis, because adequately validated methods are a necessity for approvable regulatory filings. What constitutes a validated method, however, is subject to analyst interpretation because there is no universally accepted industry practice for assay validation. This book is intended to serve as a guide to the analyst in terms of the issues and parameters that must be considered in the development and validation of analytical methods. In addition to the critical issues surrounding method validation, this book also deals with other related factors such as method development, data acquisition, automation, cleaning validation and regulatory considerations. \u003cbr\u003e\u003cp\u003eThe book is divided into three parts. Part One, comprising two chapters, looks at some of the basic concepts of method validation. Chapter 1 discusses the general concept of validation and its role in the process of transferring methods from laboratory to laboratory. Chapter 2 looks at some of the critical parameters included in a validation program and the various statistical treatments given to these parameters.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003ePart Two (Chapters 3, 4 and 5) of the book focuses on the regulatory perspective of analytical validation. Chapter 3 discusses in some detail how validation is treated by various regulatory agencies around the world, including the United States, Canada, the European Community, Australia and Japan. This chapter also discusses the International Conference on Harmonization (ICH) treatment of assay validation. Chapters 4 and 5 cover the issues and various perspectives of the recent United States vs. Barr Laboratories Inc. case involving the retesting of samples. \u003cbr\u003e\u003c\/p\u003e\u003cp\u003ePart Three (Chapters 6 - 12) covers the development and validation of various analytical components of the pharmaceutical product development process. This part of the book contains specific chapters dedicated to bulk drug substances and finished products, dissolution studies, robotics and automated workstations, biotechnology products, biological samples, analytical methods for cleaning procedures and computer systems and computer-aided validation. Each chapter goes into some detail describing the critical development and related validation considerations for each topic.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eThis book is not intended to be a practical description of the analytical validation process, but more of a guide to the critical parameters and considerations that must be attended to in a pharmaceutical development program. Despite the existence of numerous guidelines including the recent attempts by the ICH to be implemented in 1998, the practical part of assay validation will always remain, to a certain extent, a matter of the personal preference of the analyst or company. Nevertheless, this book brings together the perspectives of several experts having extensive experience in different capacities in the pharmaceutical industry in an attempt to bring some consistency to analytical method development and validation.\u003c\/p\u003e","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508026437729,"sku":"9780080427928","price":38.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_c8ac2ae9-94f8-4c26-be3d-34f22c35e866.jpg?v=1778631198"},{"product_id":"alkaloids-chemical-and-biological-perspectives-volume-11-chemical-and-biological-perspectives-volume-12","title":"Alkaloids: Chemical and Biological Perspectives, Volume 11: Chemical and Biological Perspectives, Volume 11","description":"Volume 11 of this series presents five timely reviews on current research on alkaloids. Chapter 1 by Paul L. Schiff, Jr. is a monumental survey of research that has been carried out over the past decade on the \u003ci\u003eThalictrum\u003c\/i\u003e alkaloids. Forty-six new alkaloids are described from fifteen species of the genus \u003ci\u003eThalictrum\u003c\/i\u003e, as well as 116 alkaloids of known structure from thirty-six species and subspecies of the genus. The chapter includes discussions of isolation and structure elucidation, analysis, biosynthesis, cell culture, and pharmacology. Also featured are inclusive compilations of botanical sources, alkaloids by alkaloid types, and calculated molecular weights of the \u003ci\u003eThalictrum\u003c\/i\u003e alkaloids.\u003cbr\u003e\u003cp\u003eChapter 2 by Giovanni Appendino provides a fascinating treatment of Taxine, a collective name referring to a mixture of diterpenoid alkaloids from the yew tree (genus: \u003ci\u003eTaxus\u003c\/i\u003e). Taxine is responsible for the toxic properties of the yew tree that has been documented in historical and fictional literature, from Julius Caesar to Shakespeare, and from Agatha Christie to T.S. Eliot. The chapter treats the history, isolation techniques, structure elucidation, chemistry, and pharmacology of Taxine.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eChapter 3 by Mary D. Menachery surveys the alkaloids of South American Menispermaceae (moonseed family). Many different structural types are included in this family. The alkaloid-bearing plants are woody-vines, shrubs, or small trees. Several of these species possess potent curare activity. The chemistry as well as pharmacology of these alkaloids is summarized.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eChapter 4 by Russell J. Molyneux, Robert J. Nash, and Naoki Asano treats the chemistry and biological activity of the calystegines and related \u003ci\u003enor\u003c\/i\u003etropane alkaloids. These polyhydroxylated bicyclic alkaloids represent another class of compounds that inhibit glycosidases, producing profound effects in biological systems by disrupting the essential cellular function of glycoprotein processing.\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eChapter 5, a related chapter by Robert J. Nash, Naoki Asano, and Alison A. Watson, reviews polyhydroxylated alkaloids that inhibit glycosidases. Topics covered include distribution, ecological significance and toxicity, isolation, synthesis, and biosynthesis.\u003c\/p\u003e","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508026994785,"sku":"9780080427973","price":89.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_c68d3459-1a87-4077-b83c-647a189a60e5.jpg?v=1778631202"},{"product_id":"neural-networks-and-genome-informatics-1","title":"Neural Networks and Genome Informatics","description":"This book is a comprehensive reference in the field of neural networks and genome informatics. The tutorial of neural network foundations introduces basic neural network technology and terminology. This is followed by an in-depth discussion of special system designs for building neural networks for genome informatics, and broad reviews and evaluations of current state-of-the-art methods in the field. This book concludes with a description of open research problems and future research directions.\u003cbr\u003e","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508027486305,"sku":"9780080428000","price":46.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_96ada15e-7654-4ec9-887c-17b1e869a05e.jpg?v=1778631207"},{"product_id":"alkaloids-chemical-and-biological-perspectives-volume-12-chemical-and-biological-perspectives-volume-13","title":"Alkaloids: Chemical and Biological Perspectives, Volume 12: Chemical and Biological Perspectives, Volume 12","description":"Acronycine, a potent antitumor agent, was discovered in the bark of the small Australian Rutaceous tree, \u003ci\u003eAcronychia baueri \u003c\/i\u003eSchott. This new work presents a comprehensive survey of the isolation, structure determination, methods of synthesis, and the biological properties of acronycine, as well as an account of natural and synthetic analogues of acronycine, and their biological properties.\u003cbr\u003e Solanum alkaloids were reviewed in 1990 and this book surveys the new developments (isolation procedures, structural elucidation methods) and critically updates earlier reviews.  In addition it presents the interesting chemistry and synthesis of cyclopeptide alkaloids. These cyclopeptide alkaloids have been isolated from ascidians, sea hares, and cyanobacteria.  Also included are reviews of the use of the functionalized lactam, pyroglutamic acid, as a chiral template for the synthesis of alkaloids.  The second review examines the on-line coupling of capillary electrophoresis (CE) and mass spectrometry (MS) for the analysis of alkaloid mixtures.  Finally a review of oxygenated analogs of the alkaloid Marcfortine for their potent antiparasitic activity is included at the end of this work. \u003cbr\u003e Each chapter in this volume has been reviewed by at least one expert in the field. Indexes for both subjects and organisms are provided.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508028141665,"sku":"9780080428055","price":92.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_d5181b0c-50a9-4898-891d-ac875d64f613.jpg?v=1778631211"},{"product_id":"fluorinated-materials-for-energy-conversion-1","title":"Fluorinated Materials for Energy Conversion","description":"\u003cb\u003e Fluorinated materials for energy conversion\u003c\/b\u003e offers advanced information on the application of fluorine chemistry to energy conversion materials for lithium batteries, fuel cells, solar cells and so on. Fluorine compounds and fluorination techniques have recently gained important roles in improving the electrochemical characteristics of such energy production devices. The book therefore focuses on new batteries with high performance, the improvements of cell performance and the improvement of electrode and cell characteristics. The authors present new information on the effect of fluorine and how to make use of fluorination techniques and fluorine compounds. With emphasis on recent developments, this book is suitable for students, researchers and engineers working in chemistry, materials science and electrical engineering.\u003cbr\u003e\u003cbr\u003e* Contains practical information, supported by examples\u003cbr\u003e* Provides an update on recent developments in the field\u003cbr\u003e* Written by specialists working in fluorine chemistry, electrochemistry, polymer and solid state chemistry","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508113600609,"sku":"9780080444727","price":124.0,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_c39c46b4-8380-4e12-9d8e-687fa1d4271f.jpg?v=1778631731"},{"product_id":"protein-folding-in-the-cell-1","title":"Protein Folding in the Cell","description":"This volume of \u003cb\u003eAdvances in Protein Chemistry\u003c\/b\u003e provides a broad, yet deep look at the cellular components that assist protein folding in the cell. This area of research is relatively new--10 years ago these components were barely recognized, so this book is a particularly timely compilation of current information. Topics covered include a review of the structure and mechanism of the major chaperone components, prion formation in yeast, and the use of microarrays in studying stress response. Outlines preceding each chapter allow the reader to quickly access the subjects of greatest interest. The information presented in this book should appeal to biochemists, cell biologists, and structural biologists.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508410282081,"sku":"9780120342594","price":64.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_639310bc-4963-4707-9ac9-8b4164c19afa.jpg?v=1778632187"},{"product_id":"protein-modules-and-protein-protein-interactions-1","title":"Protein Modules and Protein-Protein Interactions","description":"Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging from bioinformatics to physical chemistry, to biochemistry, with an emphasis on the structure-function relationship in protein-protein complexes involved in cellular processes including signal transduction.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* Comprehensive overview of different facets of macromolecule interactions\u003cbr\u003e* Computational and bioinformatics aspects of analyzing protein modules and their interactions\u003cbr\u003e* Emphasis on structure-function relationship in protein-protein complexes involved in cellular processes","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508417523809,"sku":"9780120342617","price":68.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_e309fa8c-54df-45a2-af78-a9fe652f1759.jpg?v=1778632193"},{"product_id":"unfolded-proteins-1","title":"Unfolded Proteins","description":"A variety of complementary techniques and approaches have been used to characterize peptide and protein unfolding induced by temperature, pressure, and solvent. \u003cb\u003eVolume 62, Unfolded Proteins\u003c\/b\u003e, assembles these complementary views to develop a more complete picture of denatured peptides and proteins. The unifying observation common to all chapters is the detection of preferred backbone confirmations in experimentally accessible unfolded states.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* Peptide and protein unfolding induced by temperature, pressure, and solvent\u003cbr\u003e* Denatured peptides and proteins\u003cbr\u003e* Detection of preferred backbone confirmations in experimentally accessible unfolded states","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508421095521,"sku":"9780120342624","price":64.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_5b6ae3c2-bbc1-4c64-8288-63242e5a9b84.jpg?v=1778632198"},{"product_id":"advances-in-carbohydrate-chemistry-and-biochemistry-1","title":"Advances in Carbohydrate Chemistry and Biochemistry","description":"Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists who integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508508487777,"sku":"9780120072576","price":96.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_e84a99df-cb9c-4bad-a34d-8437f70dbc84.jpg?v=1778632278"},{"product_id":"advances-in-carbohydrate-chemistry-and-biochemistry-3","title":"Advances in Carbohydrate Chemistry and Biochemistry","description":"Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.\u003cbr\u003e \u003cbr\u003e\u003cbr\u003e\u003cbr\u003eHigh quality comprehensive reviews covering all aspects of carbohydrate chemistry.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508615671905,"sku":"9780120072583","price":96.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_81571bef-2c8f-450f-ac87-140936fef4f8.jpg?v=1778632391"},{"product_id":"degenerate-ring-transformations-of-heterocycles-1","title":"Degenerate Ring Transformations of Heterocycles","description":"Established in 1960, \u003cb\u003eAdvances in Heterocyclic Chemistry\u003c\/b\u003e is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight to yield an understanding of how the chemistry drives the properties.\u003cbr\u003eDegenerate ring transformations of heterocycles are classified as reactions in which a heterocyclic system is converted into the same heterocyclic system. This monograph covers an authoritative, comprehensive overview of a host of degenerate ring transformations in five- and six-membered heterocycles. It shows how by the use of \u003cv\u003e15N-labeled, \u003cv\u003e13C-labeled, or selectively substituted compounds these degenerate rign transformations can be discovered and how most of the results can be explained by the Addition Nucleophile, Ring Opening, and Ring Closure [ANRORC] mechanism. Another main topic of the monograph is the occurrence of degenerate ring transformations.\u003c\/v\u003e\u003c\/v\u003e","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508857204833,"sku":"9780120207749","price":92.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_17df648a-d540-45f9-8f64-05a8095b9bf5.jpg?v=1778632679"},{"product_id":"advances-in-heterocyclic-chemistry-11","title":"Advances in Heterocyclic Chemistry","description":"Established in 1960, \u003cb\u003eAdvances in Heterocyclic Chemistry\u003c\/b\u003e is the definitive serial in the area—one of great importance to organic chemists, polymer chemists, and many biological scientists. Written by established authorities in the field, the comprehensive reviews combine descriptive chemistry and mechanistic insight and yield an understanding of how the chemistry drives the properties.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508857598049,"sku":"9780120207787","price":92.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_068bf88b-7dfe-493f-8c4f-11faffad6afe.jpg?v=1778632685"},{"product_id":"iron-sulfur-proteins-1","title":"Iron-Sulfur Proteins","description":"\u003cb\u003eAdvances in Inorganic Chemistry\u003c\/b\u003e presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bioinorganic to solid state. This acclaimed serial features reviews written by experts in the area and is an indispensable reference to advanced researchers. Each volume of \u003cb\u003eAdvances in Inorganic Chemistry\u003c\/b\u003e contains an index, and each chapter is fully referenced.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508859727969,"sku":"9780120236473","price":101.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_916d9eea-222e-4348-8608-495a71716db8.jpg?v=1778632715"},{"product_id":"heme-fe-proteins-1","title":"Heme-Fe Proteins","description":"\u003cb\u003eAdvances in Inorganic Chemistry\u003c\/b\u003e presents timely and informative summaries of the current progress in a variety of subject areas within inorganic chemistry, ranging from bioinorganic to solid state. This acclaimed serial features reviews written by experts in the area and is an indispensable reference to advanced researchers. Each volume of \u003cb\u003eAdvances in Inorganic Chemistry\u003c\/b\u003e contains an index, and each chapter is fully referenced.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508859891809,"sku":"9780120236510","price":101.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_2187ae8b-8c2f-4c64-b800-a2cc9dda14d8.jpg?v=1778632721"},{"product_id":"hormones-and-signaling-1","title":"Hormones and Signaling","description":"\u003cb\u003eHormones and Signaling\u003c\/b\u003e focuses on the mechanisms of gene regulation at the cellular level. It also describes the actions of hormones in modulating gene regulation and animal development.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* Glococorticoid and mineralcorticoid signaling\u003cbr\u003e* Orphan nuclear receptors\u003cbr\u003e* Nuclear receptor coactivators\u003cbr\u003e* Cytokines and STAT signaling\u003cbr\u003e* Coordination of cAMP signaling events through PKA anchoring\u003cbr\u003e* G protein-coupled extracellular Ca2+ (Ca2+0)-sensing receptor (CaR)\u003cbr\u003e* Pancreatic islet development\u003cbr\u003e* Genetic analysis of androgen receptors in development and disease\u003cbr\u003e* Antioprogestin regulable gene switch for induction of gene expression \u003ci\u003ein vivo\u003c\/i\u003e\u003cbr\u003e* Steroid receptor knockout model","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508861497441,"sku":"9780120329489","price":96.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_39d30ab2-a4ff-43fe-a047-ddfc7975262a.jpg?v=1778632755"},{"product_id":"roles-of-vasopressin-and-oxytocin-in-memory-processing-1","title":"Roles of Vasopressin and Oxytocin in Memory Processing","description":"\u003cb\u003eThe Roles of Vasopressin and Oxytocin in Memory Processing\u003c\/b\u003e reviews research progress in a subfield of Behavioral Pharmacology concerned with vasopressin’s (VP’s) and oxytocin (OT’s) roles in memory processing (MP). As hormones, VP is well-known for its pressor and antidiuretic action, and OT for its contribution to parturition and nursing.  As neurotransmitters, they participate in a wide variety of self- and species-preserving functions expressed at psychological, physiological and behavioral levels. \u003cbr\u003e\u003cbr\u003e\u003ca href=\"http:\/\/www.sciencedirect.com\/science\/bookseries\/10543589\"\u003eAdvances in Pharmacology\u003c\/a\u003e is available online on \u003ca href=\"http:\/\/www.sciencedirect.com\"\u003eScienceDirect\u003c\/a\u003e — full-text online of volumes 48 onwards.   \u003cbr\u003eElsevier book series on ScienceDirect gives multiple users throughout an institution simultaneous online access to an important compliment to primary research. Digital delivery ensures users reliable, 24-hour access to the latest peer-reviewed content. The Elsevier book series are compiled and written by the most highly regarded authors in their fields and are selected from across the globe using Elsevier’s extensive researcher network.   \u003cbr\u003eFor more information about the Elsevier Book Series on ScienceDirect Program, please visit:\u003cbr\u003e\u003ca href=\"http:\/\/www.info.sciencedirect.com\/bookseries\/\"\u003ehttp:\/\/www.info.sciencedirect.com\/bookseries\/\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e* Comprehensive coverage of both alternative theories and relevant research\u003cbr\u003e* Several key chapters reviewed by researchers whose studies and theories formed the subject matter of these chapters\u003cbr\u003e* Basic laboratory research focus with potential application for understanding and treating human memory disorders","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508861890657,"sku":"9780120329519","price":96.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_a425c43d-a973-4733-af14-8bd509948691.jpg?v=1778632766"},{"product_id":"virus-structure-1","title":"Virus Structure","description":"This volume covers the full spectrum of modern structural virology. Its goal is to describe the means for defining moderate to high resolution structures and the basic principles that have emerged from these studies. Among the topics covered are Hybrid Vigor, Structural Folds of Viral Proteins, Virus Particle Dynamics, Viral Gemone Organization, Enveloped Viruses and Large Viruses.\u003cbr\u003e\u003cbr\u003e* Covers viral assembly using heterologous expression systems and cell extracts\u003cbr\u003e* Discusses molecular mechanisms in bacteriophage T7 procapsid assembly, maturation and DNA containment\u003cbr\u003e* Includes information on structural studies on antibody\/virus complexes","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508866281569,"sku":"9780120342648","price":68.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_3ff91cd1-d93f-4e64-a7ca-eb81d18ffc52.jpg?v=1778632851"},{"product_id":"proteome-characterization-and-proteomics-1","title":"Proteome Characterization and Proteomics","description":"The content of this volume is designed to reach a wide audience, including those involved with relevant technologies such as electrophoresis and mass spectrometry, to those interested in how proteomics can benefit research. A wide range of techniques are discussed, each specifically designed to address different needs in proteomic analysis. The concluding chapter discusses the important issue related to handling large amounts of data accumulated in proteomic studies.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* Discusses  proteomics in the postgenomic age\u003cbr\u003e* Includes various strategies for quantitative proteomics  \u003cbr\u003e* Covers the role of MS in structural functional proteomics and proteomics in drug discovery and bioinformatics","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508866412641,"sku":"9780120342655","price":63.0,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_65958050-9583-461c-aaea-f705482a40f2.jpg?v=1778632855"},{"product_id":"protein-simulations-advances-in-protein-chemistry-1","title":"Protein Simulations: Advances in Protein Chemistry","description":"Protein Simulation focuses on predicting how protein will act in vivo.  These studies use computer analysis, computer modeling, and statistical probability to predict protein function.\u003cbr\u003e\u003cbr\u003e* Force Fields\u003cbr\u003e* Ligand Binding\u003cbr\u003e* Protein Membrane Simulation\u003cbr\u003e* Enzyme Dynamics\u003cbr\u003e* Protein Folding and unfolding simulations","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508866576481,"sku":"9780120342662","price":64.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_911520c3-8443-4429-a515-0c6dbc44bfa5.jpg?v=1778632859"},{"product_id":"cell-surface-receptors-1","title":"Cell Surface Receptors","description":"\u003cb\u003eCell Surface Receptors\u003c\/b\u003e contains an extensive discussion of cell surface receptors in 11 chapters by experts in their field. As cell surface receptors are involved in almost every aspect of signaling throughout the body, the topic has been of high interest in the community in recent years.\u003cbr\u003e\u003cbr\u003eSelected Contents:\u003cbr\u003e-Structures of Axon Guidance Molecules and Their Neuronal Receptors\u003cbr\u003e-Shared Cytokine Signaling Receptor\u003cbr\u003e-NKG2D and Related Immunoreceptors\u003cbr\u003e-Inonotropic Glutamat Receptor Recognition and Activation\u003cbr\u003e-Chemotaxis Receptors and Signaling","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508866805857,"sku":"9780120342686","price":64.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_657f1d4d-81be-4181-bceb-b1517e478827.jpg?v=1778632865"},{"product_id":"mechanisms-and-pathways-of-heterotrimeric-g-protein-signaling-1","title":"Mechanisms and Pathways of Heterotrimeric G Protein Signaling","description":"This volume in the \u003cb\u003eAdvances in Protein Chemistry\u003c\/b\u003e series features cutting-edge articles on topics in protein chemistry. This volume includes chapters on the structural basis of effector regulation and signal termination in heterotrimeric GƒÑƒnƒnproteins; How do receptors activate G proteins; Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads; Activation of G protein coupled receptors; Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells; Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteins.","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508867264609,"sku":"9780120342884","price":64.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_4d3b99b6-9f96-4d34-84aa-8841044ee0e8.jpg?v=1778632876"},{"product_id":"practical-process-research-development","title":"Practical Process Research \u0026 Development","description":"This book provides a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine\u003cbr\u003echemical, and agricultural chemical industries. Process R\u0026amp;D describes the steps taken, following synthesis and evaluation, to bring key\u003cbr\u003ecompounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are\u003cbr\u003eidentified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and\u003cbr\u003eacademicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R\u0026amp;D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent,\u003cbr\u003eand solvent selection; optimising catalytic reactions; chiral syntheses; and \"green chemistry.\" \"Practical Process Research and Development\" will be a valuable resource for researchers, managers, and graduate students.\u003cbr\u003e\u003cbr\u003e* Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of \"small molecules\"\u003cbr\u003e* Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more\u003cbr\u003e* Includes over 100 tips for rapid process development\u003cbr\u003e* Presents guidelines for implementing and troubleshooting processes\u003cbr\u003e\u003cbr\u003e","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508899147873,"sku":"9780120594757","price":59.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_e6f1cfcc-8db7-4ba1-abdd-a3215dc8d1f4.jpg?v=1778632996"},{"product_id":"ion-channels-and-disease","title":"Ion Channels and Disease","description":"Ion channels are membrane proteins that act as gated pathways for the movement of ions across cell membranes. They play essential roles in the physiology of all cells. In recent years, an ever-increasing number of human and animal diseases have been found to result from defects in ion channel function. Most of these diseases arise from mutations in the genes encoding ion channel proteins, and they are now referred to as the channelopathies.\u003cbr\u003e\u003cb\u003eIon Channels and Disease\u003c\/b\u003e provides an informative and up-to-date account of our present understanding of ion channels and the molecular basis of ion channel diseases. It includes a basic introduction to the relevant aspects of molecular biology and biophysics and a brief description of the principal methods used to study channelopathies. For each channel, the relationship between its molecular structure and its functional properties is discussed and ways in which genetic mutations produce the disease phenotype are considered. \u003cbr\u003eThis book is intended for research workers and clinicians, as well as graduates and advanced undergraduates. The text is clear and lively and assumes little knowledge, yet it takes the reader to frontiers of what is currently known about this most exciting and medically important area of physiology.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* Introduces the relevant aspects of molecular biology and biophysics\u003cbr\u003e* Describes the principal methods used to study channelopathies\u003cbr\u003e* Considers single classes of ion channels with summaries of the physiological role, subunit composition, molecular structure and chromosomal location, plus the relationship between channel structure and function\u003cbr\u003e* Looks at those diseases associated with defective channel structures and regulation, including mutations affecting channel function and to what extent this change in channel function can account for the clinical phenotype","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508919922785,"sku":"9780120653102","price":53.75,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_783f25b4-c804-464b-826b-e4edacd6f14c.jpg?v=1778633020"},{"product_id":"foundations-of-structural-biology","title":"Foundations of Structural Biology","description":"Imagine trying to understand an engine without visualizing its moving parts. Biological processes involve far more complex chemical reactions and components than any engine. Furthermore, the parts work together to do many more functions than an engine which sole task is to turn a shaft.    Understanding the implications of the three-dimensional coordinates for a molecule with several thousand atoms requires an understanding of, and practice with, 3D imaging.  For many biologists, this means acquiring a whole new set of skills. \u003cb\u003eFoundations of Structural Biology\u003c\/b\u003e is aimed at helping the reader develop visualization skills for protein or DNA segments, while also describing the fundamental principles underlying the organization and interaction between these complex molecules.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* Explains how to use coordinate databases and atomic coordinates of biological macromolecules\u003cbr\u003e* Teaches the skills of stereoviewing\u003cbr\u003e* Contains computer-generated stereographics\u003cbr\u003e* Describes the principles of symmetry and handedness in proteins and DNA\u003cbr\u003e* Introduces metal and lipid binding proteins and DNA-protein interactions\u003cbr\u003e* Explains the principles involved in understanding secondary and quaternary structure \u003cbr\u003e* Includes coverage of protein-metal, protein-nucleic acid, and protein-lipid interactions","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508953509985,"sku":"9780120777006","price":32.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_8d374402-c657-4d9d-92e0-37307040ace5.jpg?v=1778633055"},{"product_id":"high-resolution-nmr-theory-and-chemical-applications","title":"High Resolution NMR: Theory and Chemical Applications","description":"\u003cb\u003eHigh Resolution NMR\u003c\/b\u003e provides a broad treatment of the principles and theory of nuclear magnetic resonance (NMR) as it is used in the chemical sciences.  It is written at an \"intermediate\" level, with mathematics used to augment, rather than replace, clear verbal descriptions of the phenomena. The book is intended to allow a graduate student, advanced undergraduate, or researcher to understand NMR at a fundamental level, and to see illustrations of the applications of NMR to the determination of the structure of  small organic molecules and macromolecules, including proteins. Emphasis is on the study of NMR in liquids, but the treatment also includes high resolution NMR in the solid state and the principles of NMR imaging and localized spectroscopy. \u003cbr\u003eCareful attention is given to developing and interrelating four approaches - steady state energy levels, the rotating vector picture, the density matrix, and the product operator formalism. The presentation is based on the assumption that the reader has an acquaintance with the general principles of quantum mechanics, but no extensive background in quantum theory or proficiency in mathematics is required. Likewise, no previous background in NMR is assumed, since the book begins with a description of the basic physics, together with a brief account of the historical development of the field.\u003cbr\u003eThis third edition of High Resolution NMR preserves the \"conversational\" approach of the previous editions that has been well accepted as a teaching tool. However, more than half the material is new, and the remainder has been revised extensively. Problems are included to reinforce concepts in the book.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* Uses mathematics to augment, not replace, verbal explanations \u003cbr\u003e* Written in a clear and conversational style \u003cbr\u003e* Follows the successful format and approach of two previous editions\u003cbr\u003e* Revised and updated extensively--about 70 percent of the text is new\u003cbr\u003e* Includes problems and references to additional reading at the end of each chapter","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44508984868961,"sku":"9780120846627","price":57.5,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_16c90171-c4fc-43ff-bcd3-86534b75264d.jpg?v=1778633092"}],"url":"https:\/\/ebooks.aafaqeducation.com\/collections\/bisac-biochemistry.oembed?page=12","provider":"ebook.aafaqeducation","version":"1.0","type":"link"}