{"product_id":"pnh-and-the-gpi-linked-proteins","title":"PNH and the GPI-Linked Proteins","description":"Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients.\u003cbr\u003eWritten by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins.\u003cbr\u003eThis unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins.\u003cbr\u003e\u003cbr\u003eKey Features\u003cbr\u003e* Outlines the chemical features of PNH\u003cbr\u003e* Explains the mechanism of hemolysis\u003cbr\u003e* Includes work on the biochemistry of glycophosphoinositol anchors\u003cbr\u003e* Contains descriptions of the chemistry and biophysics of GPI-anchored proteins","brand":"Elsevier S \u0026 T","offers":[{"title":"perpetual","offer_id":44517836161121,"sku":"9780127729404","price":59.25,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0268\/9869\/4241\/files\/480_61ee2947-82c0-4f31-a377-d7c309998963.jpg?v=1778718732","url":"https:\/\/ebooks.aafaqeducation.com\/products\/pnh-and-the-gpi-linked-proteins","provider":"ebook.aafaqeducation","version":"1.0","type":"link"}