Elsevier S & T

Advances in Cancer Research

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Table of contents
  • Copyright Pageiv
  • Contentsv
  • Contributors to Volume 82vii
  • Chapter 1. Retinoblastoma Protein Partners1
  • I. An Introduction to pRb-Binding Proteins2
  • II. Potential pRb Partners13
  • References47
  • Chapter 2. p53-Dependent Apoptosis Pathways55
  • I. p5356
  • II. Bcl-2 Family62
  • III. Caspase Family67
  • IV. IAPs74
  • V. p53-Mediated Apoptosis in Cancer Therapy75
  • References76
  • Chapter 3. von Hippel-Lindau Disease: Clinical and Molecular Perspectives85
  • I. The VHL Gene and VHL Disease86
  • II. The VHL TSG and Sporadic Cancers94
  • III. Functional Analysis of The VHL Tumor Suppressor Gene95
  • IV. Conclusion101
  • References101
  • Chapter 4. Nitric Oxide-Induced Apoptosis in Tumor Cells107
  • I. Introduction108
  • II. NO and Antimetastatic Resistance109
  • III. Mechanisms of NO-Mediated Apoptosis116
  • IV. Concluding Remarks124
  • References125
  • Chapter 5. Detection of Minimal Residual Disease133
  • I. Introduction134
  • II. Technical Aspects of the Detection of Minimal Residual Disease135
  • III. MRD in Leukemia143
  • IV. MRD in Lymphoma157
  • V. MRD in Solid Tumors165
  • VI. Concluding Remarks170
  • References172
  • Chapter 6. Modeling Prostate Cancer in the Mouse187
  • I. Introduction187
  • II. Anatomy of the Adult Prostate Gland188
  • III. Embryology and Growth of the Prostate Gland189
  • IV. Components of the Epithelial Compartment: Do Prostate Stem Cells Exist?192
  • V. Role of Oncogenes and Tumor Suppressors in Prostate Neoplasia194
  • VI. Progress in the Development of CaP Animal Models197
  • References201
  • Chapter 7. Immunity to Oncogenic Human Papillomaviruses205
  • I. Epidemiology of Human Papillomavirus Infection206
  • II. The Antibody Response to HPV Infection207
  • III. Cellular Immunity to HPV Infection214
  • IV. Does Cross-Protective Immunity Exist?226
  • References231
  • Index239
Book details
  • Vendor Elsevier S & T
  • SKU 9780120066827
  • ISBN-13 9780080490236

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Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including nitric oxide-induced apoptosis in tumor cells, detection of minimal residual disease, immunity to oncogenetic human papilloma viruses, and modeling prostate cancer in the mouse.