ADVANCES IN CANCER RESEARCH, VOLUME 3
Regular price
27.000 KD
inc. VAT
Couldn't load pickup availability
Table of contents
- Contentsix
- Chapter 1. Etiology of Lung Cancer1
- I. Introduction1
- II. Increase in Incidence2
- III. Etiological Factors8
- IV. Conclusion46
- References47
- Chapter 2. The Experimental Development and Metabolism of Thyroid Gland Tumors51
- I. Introduction52
- II. Thyroid Gland Biochemistry and Metabolism53
- III. Spontaneous Thyroid Tumors56
- IV. Effect of Goitrogens and Iodine on Body Weight, and Thyroid Weight58
- V. Induction of Thyroid Gland Cancer by Chemical Carcinogens60
- VI. Dietary Iodine Deficiency and Experimental Development of Thyroid Tumors60
- VII. Goitrogen-Induced Thyroid Gland Tumors in Mice62
- VIII. Transplantability of Thyroid Gland Tumors in Mice62
- IX. Thyroid-Pituitary Interrelationships65
- X. Effects of Ionizing Radiations in Thyroid Gland Carcinogenesis68
- XI. Experimental Thyroid Tumors in Rats Produced by Goitrogens and Carcinogens75
- XII. Transplantability and Metabolism of Rat Thyroid Gland Tumors81
- XIII. Biochemistry of Thyroid Gland Tumors in Mice86
- XIV. Thyroid Gland Cancer in Man102
- XV. Summary and Conclusions109
- References112
- Chapter 3. Electronic Structure and Carcinogenic Activity and Aromatic Molecules New Developments117
- I. Introduction117
- II. The Localization Theory of Chemical Reactions118
- III. Electronic Structure and Carcinogenic Activity of Unsubstituted Polynuclear Hydrocarbons122
- IV. Extension of the Theory to Substituted Derivatives of Polycylic Hydrocarbons149
- V. General Conclusions and Suggestions156
- Appendix. The Metabolic Reactivity of Carcinogenic Hydrocarbons161
- References167
- Chapter 4. Some Aspects of Carcinogenesis171
- I. Introduction171
- II. Cancer as a Regressive Process in General Pathology172
- III. The Energy Changes in Carcinogenesis (The Concept of Entropy in Pathology)174
- IV. The Supposed Significance of Derangements of Oxidative Metabolism in Carcinogenesis180
- V. The Interaction between Some Carcinogenic Agents and Cell Constituents185
- VI. Cancer as a Problem of Protein Chemistry194
- VII. Summary213
- References214
- Chapter 5. Pulmonary Tumors in Experimental Animals223
- I. Historical Introduction223
- II. Frequency and Distribution of Pulmonary Tumors in Mice225
- III. Pulmonary Tumors in Other Animals227
- IV. Morphology and Biochemistry of Pulmonary Tumors in Mice229
- V. Histogenesis of Pulmonary Tumors in Mice233
- VI. Influence of Heredity in Pulmonary Tumors in Mice235
- VII. Polycyclic Hydrocarbons and Related Compounds237
- VIII. Urethane and Related Compounds242
- IX. Other Chemical and Physical Agents, Including Inhalants244
- X. Factors Affecting Pulmonary Tumor Induction in Mice248
- XI. Mechanism of Induction of Pulmonary Tumors in Mice252
- XII. Pulmonary Tumors in Man and General Discussion256
- References261
- Chapter 6. Oxidative Metabolism of Neoplastic Tissues269
- I. The Concepts of Warburg270
- II. The Pasteur Effect274
- III. Present Concept of Carbohydrate Oxidation278
- IV. β-Oxidation of Fatty Acids282
- V. Mechanisms of Glycolysis in Tumors283
- VI. Electron Transport in Tumors288
- VII. Oxidation in Tumor Homogenates315
- References323
- Index339
ADVANCES IN CANCER RESEARCH, VOLUME 3