Advances in Drug Research
Regular price
55.500 KD
inc. VAT
Couldn't load pickup availability
Table of contents
- Contentsv
- Contributorsvii
- Preface: "The Search for Consensus"viii
- Chapter 1. Peptidomimetics in Drug Design1
- 1 Introduction1
- 2 Design of Peptidomimetics3
- 3 Strategies for the Development of Peptidomimetics7
- 4 Examples of Peptidomimetics23
- 5 Summary and Outlook63
- References66
- Chapter 2. Medicinal Photochemistry: Phototoxic and Phototherapeutic Aspects of Drugs79
- 1 Introduction81
- 2 Phototoxic Drugs and other Xenobiotics106
- 3 Phototherapeutics135
- 4 Conclusions157
- References157
- Chapter 3. Development of Estrogen Antagonists as Pharmaceutical Agents171
- 1 Introduction172
- 2 Role of Estrogens In Nature173
- 3 Mechanisms of Action of Estrogen Antagonists174
- 4 ELA In Fertility Regulation178
- 5 Antiestrogens for the Treatment of Cancer204
- 6 Estrogen Antagonists in the Management of Osteoporosis237
- 7 Miscellaneous245
- 8 Conclusion251
- Acknowledgement252
- References252
- Chapter 4. Peroxidic Antimalarials271
- 1 Introduction271
- 2 The Advent of Peroxidic Antimalarials276
- 3 Assays for Antimalarial Activity278
- 4 Naturally Occurring Antimalarial Trioxanes and Peroxides279
- 5 Semi-synthetic Artemisinin Derivatives293
- 6 Various Synthetic Hydroperoxides and Peroxides301
- 7 Synthetic Bridged Bicyclic Peroxides303
- 8 Synthetic Tricyclic 1,2,4-Trioxanes305
- 9 Synthetic Bicyclic 1,2,4-Trioxanes309
- 10 Mode of Action312
- 11 Design of Future Peroxidic Antimalarial Drugs319
- 12 Concluding Remarks320
- References320
- Subject Index326
- Cumulative Index of Authors336
- Cumulative Index of Titles339
This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes. In line with the tradition of the series, chapters on general themes are interspersed with chapters on specific drug classes and targets.