Advances in Genetics
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Table of contents
- Contentsv
- Contributorsvii
- Chapter 1. Targeted Expression of Tetanus Toxin: A New Tool to Study the Neurobiology of Behavior1
- I. Introduction2
- II. Mechanism and Action of Tetanus Toxin Light Chain4
- III. From Electrophysiology to Behavior11
- IV. Dissecting Behavior12
- V. Conclusions and Perspectives32
- References35
- Chapter 2. Germline Transformants Spreading Out to Many Insect Species49
- I. Introduction: The Continuing Relevance of Genetic Transformation Technologies in the Genomics Era50
- II. Handling Nondrosophilid Insects53
- III. The P Element Paradigm Is Successful in Non-Drosophilids, but Not with P Elements54
- IV. Transformation of Nondrosophilid Insects by Transposable Elements57
- V. Insect Transformation and Genetic Analysis68
- VI. Promoter Analysis in Transgenic Insects69
- VII. Concluding Remarks: Generic Technologies and Insect Genetics77
- References78
- Chapter 3. Genes Mediating Sex-Specific Behaviors in Drosophila87
- I. Introduction87
- II. The Single-Gene Approach90
- III. Sex Determination Genes Direct Morphology, Biochemistry, and Behavior92
- IV. The Brain as a Sexual Organ102
- V. The Role of Serotonin103
- VI. Sexual Conflict104
- VII. Conclusions109
- References110
- Chapter 4. Evolutionary Behavioral Genetics in Drosophila117
- I. Introduction118
- II. Clock Genes119
- III. Genes Involved in Sexual Behavior126
- IV. Conclusion and Perspectives139
- References140
- Index151
Advances in Genetics increases its focus on modern human genetics and its relation to medicine with the merger of this long-standing serial with Molecular Genetic Medicine. This merger affirms the Academic Press commitment to publish important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.
Genetics, the science of heredity, lies at the heart of biology, and many diseases are impacted by an individuals genetic make-up. The field of genetics is rapidly evolving and new medical break-throughs are occurring as a result of advances in knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. This volume of Advances in Genetics contains the following articles: Targeted Expression of Tetanus Toxin; Germ-line Transformants Spreading Out to Many Insect Species; Genes Mediating Sex-Specific Behaviors in Drosophila; and Evolutionary Analyses of Genes and Their Functional Implications.
Genetics, the science of heredity, lies at the heart of biology, and many diseases are impacted by an individuals genetic make-up. The field of genetics is rapidly evolving and new medical break-throughs are occurring as a result of advances in knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. This volume of Advances in Genetics contains the following articles: Targeted Expression of Tetanus Toxin; Germ-line Transformants Spreading Out to Many Insect Species; Genes Mediating Sex-Specific Behaviors in Drosophila; and Evolutionary Analyses of Genes and Their Functional Implications.