Elsevier S & T

Advances in Immunology

Dixon, Frank J.

In stock
No reviews
72.250 KD inc. VAT
License
Table of contents
  • Contentsv
  • Contributorsix
  • Chapter 1. The Actin Cytoskeleton, Membrane Lipid Microdomains, and T Cell Signal Transduction1
  • I. Introduction1
  • II. Overview of T Cell Signaling3
  • III. Lipid Rafts16
  • IV. Actin Cytoskeleton23
  • V. Actin Dynamics in Signal TransductionŒGeneral Principles30
  • VI. Conclusion34
  • References35
  • Chapter 2. Raft Membrane Domains and Immunoreceptor Functions45
  • I. Introduction45
  • II. Lipid Raft Concept: Bridging Biophysics to Biology46
  • III. Immunoreceptor Signaling and Raft Domains54
  • IV. Outlook79
  • References79
  • Chapter 3. Human Basophils: Mediator Release and Cytokine Production93
  • I. Introduction93
  • II. Basophil Growth and Maturation94
  • III. Cell Surface Markers94
  • IV. Inflammatory Mediators98
  • V. Basophil Activation101
  • VI. Signal Transduction and Pharmacological Control of Secretion106
  • VII. Basophils and Allergic Disease112
  • References114
  • Chapter 4. Btk and BLNK in B Cell Development123
  • I. Introduction123
  • II. Btk and B Cell Development124
  • III. Activation of Btk129
  • IV. Downstream of Btk137
  • V. BLNK Connects Btk Activity to Downstream Effectors142
  • VI. Conclusion150
  • References151
  • Chapter 5. Diversity and Regulatory Functions of Mammalian Secretory Phospholipase A2s163
  • I. Introduction163
  • II. Structures and Enzymatic Properties of sPLA2s164
  • III. Expression and Functions of sPLA2s169
  • IV. sPLA2 Receptors182
  • V. Conclusion183
  • References184
  • Chapter 6. The Antiviral Activity of Antibodies in Vitro and in Vivo195
  • I. Introduction195
  • II. Mechanisms of Neutralization196
  • III. Complement-Mediated Virolysis225
  • IV. Antibody-Mediated Phagocytosis226
  • V. Antibody-Mediated Cytotoxicity226
  • VI. Intracellular Neutralization227
  • VII. Mechanisms of Antibody Protection in Vivo227
  • VIII. Mechanisms of Antiviral Antibody Activity in Established Infection241
  • IX. Observations with Nonviral Pathogens244
  • X. Conclusions244
  • References248
  • Chapter 7. Mouse Models of Allergic Airway Disease263
  • I. Introduction263
  • II. Conclusion287
  • References287
  • Chapter 8. Selected Comparison of Immune and Nervous System Development297
  • I. Introduction297
  • II. Major Cellular Components of the Nervous System297
  • III. Embryonic Divisions of the Nervous System299
  • IV. Embryonic Development of the Cerebral Cortex303
  • V. Ventricular Zone Neuroblast Programmed Cell Death309
  • VI. Nonhomologous End-Joining and DNA Rearrangement313
  • VII. Conclusion316
  • References317
  • Index323
  • Contents of Recent Volumes333
Book details
  • Vendor Elsevier S & T
  • SKU 9780120224777
  • ISBN-13 9780080493626
  • Author Dixon, Frank J.
  • Category Medical
  • Subject Immunology

Do you have questions about this book?

Ask an expert!

Description eBook delivery & access Reviews
Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.