Advances in Planar Lipid Bilayers and Liposomes
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Table of contents
- Contentsv
- Prefacexi
- Contributorsxiii
- Chapter One. Stabilization of Hydrophilic Pores in Charged Lipid Bilayers by Anisotropic Membrane In1
- 1. Introduction2
- 2. Geometrical Model of Hydrophilic Pore3
- 3. Free Energy of the System4
- 4. Electrostatic Energy of the Pore6
- 5. Free Energy of the Inclusions10
- 6. Theoretical Predictions14
- 7. On the Role of Anisotropic Membrane Inclusions in Membrane Electroporation-Experimental Considera19
- 8. Discussion and Conclusions21
- References23
- Chapter Two. Rapid Purification and Reconstitution of Recombinant Voltage-Gated Sodium Channels into27
- 1. Voltage-Gated Sodium Channels28
- 2. Algal Toxins that Modulate Sodium Channel Activity29
- 3. Ion Channels in Bilayer Lipid Membrane Biosensors30
- 4. Ion Channel Purification31
- 5. Methods33
- 6. Functional Reconstitution39
- 7. Conclusion43
- Acknowledgements44
- References44
- Chapter Three. Insights in the Organization and Dynamics of Erythrocyte Lipid Rafts49
- 1. The Erythrocyte Membrane51
- 2. Lipid Rafts52
- 3. DRMs of the Erythrocyte Membrane57
- 4. Exovesiculation of Erythrocytes66
- 5. Lipid Rafts of Erythrocytes: Hypothetical Considerations70
- 6. Conclusions75
- References75
- Chapter Four. Interactions of Erythroid and Nonerythroid Spectrins and Other Membrane-Skeletal Prote81
- 1. Introduction82
- 2. Spectrin-Based Membrane Skeleton83
- 3. Interactions of Erythroid and Nonerythroid Spectrins with Lipid Mono- and Bilayers andother Amphi84
- 4. 4. Spectrin–Lipid Interactions; a Molecular Approach89
- 5. Interactions of Other Skeletal Proteins with Membrane Mono- and Bilayers95
- 6. Concluding Remarks97
- Acknowledgements97
- References97
- Chapter Five. Liposome-Based Biomembrane Mimetic Systems: Implications for Lipid–Peptide Interacti103
- 1. Introduction104
- 2. Understanding the Mechanism of Lipid-Peptide Interaction110
- 3. General Aspects of Model Membranes117
- 4. X-ray Diffraction in Combination with a Global Data Analysis121
- 5. Bacterial Model Membranes125
- 6. 6. The Antimicrobial Peptide LF11 – Influence of N- Acylation127
- 7. Structural Information on Coexisting Membrane Domains130
- 8. Outlook132
- References132
- Chapter Six. Application of Spin-Labeling EPR and ATR-FTIR Spectroscopies to the Study of Membrane H139
- 1. Introduction140
- 2. Experimental Methods to Approach Membrane Heterogeneity142
- 3. Membrane Hydration149
- 4. Membrane Heterogeneity Characterization by SL-EPR152
- 5. Membrane Heterogeneity Characterization by ATR–FTIR Spectroscopy157
- 6. Conclusions160
- Acknowledgements160
- References161
- Chapter Seven. Electroporation of Planar Lipid Bilayers and Membranes165
- 1. Introduction167
- 2. Experimental Investigation of Electroporation on Planar Lipid Bilayers169
- 3. Attempts of Theoretical Explanation of Electroporation175
- 4. Electroporation of Cells-Experimental Observations and Analysis of Underlying Phenomena194
- 5. Comparison between Planar Lipid Bilayers and Cell Electroporation211
- Appendix A213
- Appendix B217
- References219
- Chapter Eight. Cytoskeletal Proteins at the Lipid Membrane227
- 1. Introduction228
- 2. Stopped-Flow Spectrophotometer229
- 3. Differential Scanning Calorimetry (DSC)233
- 4. Solid-State NMR Spectroscopy238
- 5. Fluorescence Recovery after Photobleaching (FRAP)244
- Acknowledgements251
- References251
- Subject Index257
- Color Section259
Advances in Planar Lipid Bilayers and Liposomes, Volume 6, continues to include invited chapters on a broad range of topics, covering both main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results in this exciting multidisciplinary field of their own research group.
Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is the
further development of this interdisciplinary field worldwide.
* Contributions from newcomers and established and experienced researchers
* Exploring theoretically and experimentally the planar lipid bilayer systems and spherical liposomes
* This volume is dedicated to mark the Bilayer Lipid Membranes 45th anniversary
Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is the
further development of this interdisciplinary field worldwide.
* Contributions from newcomers and established and experienced researchers
* Exploring theoretically and experimentally the planar lipid bilayer systems and spherical liposomes
* This volume is dedicated to mark the Bilayer Lipid Membranes 45th anniversary