Biology at the Single Molecule Level

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Table of contents
  • Contentsv
  • Editorial: Single-molecule biochemistry coming of agevii
  • Part I: (reprinted from Progress in Biophysics & Molecular Biology 74 / 1-2)ix
  • Chapter 1. Protein structural dynamics by single-molecule fluorescence polarization1
  • Chapter 2. Single molecule force spectroscopy in biology using the atomic force microscope37
  • Chapter 3. Mechanical design of proteins studied by single-molecule force spectroscopy and protein e63
  • Chapter 4. The importance of molecular structure and conformation: learning with scanning probe micr93
  • Chapter 5. Twisting and stretching single DNA molecules115
  • Part II: (reprinted from Progress in Biophysics & Molecular Biology 77/1)141
  • Chapter 1. Single molecule measurements of titin elasticity143
  • Chapter 2. Analyses of single-molecule mechanical recordings: application to actomyosin interactions187
  • Chapter 3. Structural and functional imaging with carbon nanotube AFM probes215
Book details
  • Vendor Elsevier S & T
  • SKU 9780080440316
  • ISBN-13 9780080560618

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This is the first book solely devoted to single-molecule biochemistry and molecular biology. Authors were selected on the basis of their contribution to this new and exciting field, and were asked to focus more on the biological problems that can be approached using single-molecule techniques rather than on the techniques per se. It is thought that such techniques will eventually dominate the physical characterization of biologically important macromolecules.