Biosensors: Kinetics of Binding and Dissociation Using Fractals: Kinetics of Binding and Dissociation Using Fractals
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Table of contents
- Cover
- Contentsxi
- Forewordvii
- Prefaceix
- Chapter 1. Introduction1
- 1.1 Definition and Expanding Needs of Biosensors1
- 1.2 Advantages and Disadvantages of Biosensors4
- 1.3 Newer Applications: Present and Future8
- 1.4 Biosensor Economics10
- 1.5 Overview13
- References14
- Chapter 2. Effect of Reynolds Number on Fractal Binding Kinetics on a Surface-Based Biosensor17
- 2.1 Introduction17
- 2.2 Theory18
- 2.3 Results20
- 2.4 Boundary Layer Analysis and Sherwood Number25
- 2.5 Conclusions27
- References28
- Chapter 3. DNA Fractal Binding and Dissociation Kinetics31
- 3.1 Introduction31
- 3.2 Theory34
- 3.3 Results36
- 3.4 Conclusions52
- References54
- Chapter 4. Fractal Analysis of Binding and Dissociation Interactions of Estrogen Receptors to Ligand57
- 4.1 Introduction57
- 4.2 Theory59
- 4.3 Results61
- 4.4 Conclusions82
- References84
- Chapter 5. A Fractal Analysis of Analyte–Estrogen Receptor Binding and Dissociation Kinetics Using85
- 5.1 Introduction85
- 5.2 Theory88
- 5.3 Results90
- 5.4 Conclusions103
- References105
- Chapter 6. A Fractal Analysis of Analyte–Estrogen Receptor Binding and Dissociation Kinetics Using107
- 6.1 Introduction107
- 6.2 Theory110
- 6.3 Results113
- 6.4 Conclusions130
- References131
- Chapter 7. Fractal Analysis of Binding Interactions of Nuclear Estrogen Receptors Occurring on Biose133
- 7.1 Introduction133
- 7.2 Theory136
- 7.3 Results137
- 7.4 Conclusions155
- References157
- Chapter 8. A Kinetic Study of Analyte–Receptor Binding and Dissociation for Biosensor Applications159
- 8.1 Introduction159
- 8.2 Theory162
- 8.3 Results167
- 8.4 Conclusions179
- References180
- Chapter 9. The Temporal Nature of the Binding and Dissociation Rate Coefficients and the Affinity Va183
- 9.1 Introduction183
- 9.2 Theory185
- 9.3 Results189
- 9.4 Conclusions200
- References202
- Chapter 10. Fractal Analysis of Analyte–Receptor Binding and Dissociation, and Dissociation Alone205
- 10.1 Introduction205
- 10.2 Theory208
- 10.3 Results212
- 10.4 Conclusions227
- References228
- Chapter 11. Fractal Analysis of Cellular Analyte–Receptor Binding and Dissociation on Biosensors233
- 11.1 Introduction233
- 11.2 Theory237
- 11.3 Results241
- 11.4 Conclusions259
- References260
- Chapter 12. Analyte–Receptor Binding Kinetics on Microarrays: A Fractal Analysis265
- 12.1 Introduction265
- 12.2 Theory267
- 12.3 Results268
- 12.4 Conclusions290
- References292
- Chapter 13. Analyte–Receptor Binding on SPR Biosensors: A Fractal Analysis of Cre–loxP Interacti295
- 13.1 Introduction295
- 13.2 Theory296
- 13.3 Results300
- 13.4 Conclusions313
- References314
- Chapter 14. Binding and Dissociation Kinetic Using Fractals: An Analysis of Electrostatic Effects an317
- 14.1 Introduction317
- 14.2 Theory318
- 14.3 Results320
- 14.4 Conclusions337
- References338
- Chapter 15. A Study of Analyte–Receptor Binding and Dissociation on Biosensor Surfaces: A Fractal339
- 15.1 Introduction339
- 15.2 Theory341
- 15.3 Results344
- 15.4 Conclusions357
- References359
- Chapter 16. Fractal Analysis of Analyte–Receptor Binding and Dissociation Kinetics in Microcantile361
- 16.1 Introduction361
- 16.2 Theory362
- 16.3 Results364
- 16.4 Conclusions383
- References385
- Subject Index389
This title brings to the attention of researchers in the industry, and in academia, the application of fractals to help in modeling the analyte/receptor binding and dissociation kinetics on biosensor surfaces.
The work builds on that done in Engineering Biosensors: Kinetics and Design Applications, published by Academic Press in 2002. In particular, more examples are provided of where biosensors may be effectively used. This sequel is extremely timely, given the anticipation that the applications and reliance on biosensors will increase due to the advances in miniaturization, (wireless) communications, and the development of new materials (especially biological and chemical). Other applications of biosensors on the increase can be found in: the protection of civilian structures and infrastructures; protection from possible biological and chemical threats; health care; energy; food safety; and the environment to name a few.
- Covers all areas of applications of biosensors
- No other book on biosensors describes the kinetics of binding
- Provides numerous examples of where biosensors may be used
The work builds on that done in Engineering Biosensors: Kinetics and Design Applications, published by Academic Press in 2002. In particular, more examples are provided of where biosensors may be effectively used. This sequel is extremely timely, given the anticipation that the applications and reliance on biosensors will increase due to the advances in miniaturization, (wireless) communications, and the development of new materials (especially biological and chemical). Other applications of biosensors on the increase can be found in: the protection of civilian structures and infrastructures; protection from possible biological and chemical threats; health care; energy; food safety; and the environment to name a few.
- Covers all areas of applications of biosensors
- No other book on biosensors describes the kinetics of binding
- Provides numerous examples of where biosensors may be used