Bioseparation Engineering
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Table of contents
- Bioseparation Engineeringiii
- Copyright Pageiv
- Contentsix
- Prefacev
- Acknowledgmentsvii
- Chapter 1. Adsorption, Chromatography and Membrane Separations1
- Recent Advances in Membrane Technology that Could Improve Resource Recovery and Recycle: Fluid Mecha3
- Stabilization of Target Protein during Bioseparation9
- Bioseparation of Natural Products15
- On-line Recovery of Large Molecules from Mixture Solution Using Semi-continuous Size Exclusion Chrom21
- Dye Adsorption by Activated Carbon in Centrifugal Field25
- Formation and Structural Change of Cake during Crossflow Microfiltration of Microbial Cell Suspensio29
- Continuous Separation of Ternary Mixture of Amino Acids Using Rotating Annular Chromatography with P35
- Mass Transfer Characteristics of a Perfusion-type Gel Analyzed by Shallow Bed Method41
- Fouling of Cheese Whey during Reverse Osmosis and Precipitation of Calcium Phosphate47
- Separation of Dead Cells from Culture Broth by Using Dielectrophoresis53
- Microcalorimetric Studies of Interactions between Proteins and Hydrophobic Ligands in Hydrophobic In59
- Membrane Phase Separation of Aqueous/Alcohol Biphase Mixture and Its Application for Enzyme Bioreact63
- Microfabricated Structures for Bioseparation69
- Production of a Human IgM-type Antibody and Preparation of Combinatorial Library by Recombinant Sacc75
- Dynamic Binding Performance of Large Biomolecules such as y-globulin, Viruses and Virus-like Particl81
- Effects of Swelling Pressure of Resin and Complex Formation with a Counter-ion on the Apparent Distr87
- Separation Behavior of Proteins near the Isoelectric Points in Electrostatic Interaction (Ion Exchan93
- Chapter 2. Refolding Processes for Protein99
- Large-scale Refolding of Therapeutic Proteins101
- Novel Method for Continuous Refolding of Protein with High Efficiency107
- Novel Protein Refolding by Reversed Micelles113
- Development of Efficient Protein Refolding Systems Using Chaperonins119
- Monitoring Structural Changes of Proteins on Solid Phase Using Surface Plasmon Resonance Sensor125
- Chapter 3. Partitioning and Extraction131
- Recent Advances in Reversed Micellar Techniques for Bioseparation133
- A Novel Method of Determining the Aggregation Behavior of Microemulsion Droplets137
- Preparation of Temperature-sensitive Antibody Fragments143
- Stability Enhancement of a-amylase by Supercritical Carbon Dioxide Pretreatment149
- Behavior of Monodispersed Oil-in Water Microsphere Formation Using Microchannel Emulsification Techn155
- Chapter 4. Bioseparation Engineering for Global Environment161
- Domestic Wastewater Treatment Using a Submerget Membrane Bioreactor163
- Biosorption of Heavy Metal Ion with Penicillin Biomass169
- Removal of Cadmium Ion175
- The Effects of Additives on Hydrolysis of Cellulose with Water under Pressures181
- Removal of Volatile Organic Compounds from Waste Gas in Packed Column with Immobilized Activated Slu187
- Chapter 5. Industrial Separation Processes and Validations193
- Validation of Bioprocess Chromatography : Principles and Practices195
- Column Qualification in Process Ion-exchange Chromatography201
- Characterization of Phage Encoded Lysis Proteins and Its Applications for Cell Disruption207
- Recovery of Poly-b-hydroxybutyrate from Recombinant Escherichia coli by a Combined Biologi-chemical213
- Cleaning Liquid Consumption and Recycle of Biopharmaceutical Plant219
- Index of authors225
The bioseparation engineering of today includes downstream process engineering such as waste water, material and gas treatment. Taking this tendency into account, bioseparation engineers gathered in Japan as a special research group under the main theme of "Recovery and Recycle of Resources to Protect the Global Environment".
The scope of this book is based on the conference, and deals not only with recent advances in bioseparation engineering in a narrow sence, but also the environmental engineering which includes waste water treatment and bioremediation. The contributors of this book cover many disciplines such as chemical engineering, analytical chemistry, biochemistry, and microbiology.
Bioseparation Engineering will stimulate young engineers and scientists who will develop bioseparation engineering further in the 21st century, and contribute to a world-wide attention to the global environment