Current Topics in Cellular Regulation
Regular price
63.000 KD
inc. VAT
Couldn't load pickup availability
Table of contents
- Current Topics in Cellular Regulationiii
- Copyright Pageiv
- Contentsv
- Chapter 1. Regulatory Features of Multicatalytic and 26S Proteases1
- I. Introduction1
- II. Structural and Enzymatic Properties of MCP2
- III. Structural and Enzymatic Properties of 26S Protease5
- IV. Regulation of MCP and 26S Protease8
- V. Regulation by MCP and 26S Proteases22
- VI. Summary26
- References26
- Chapter 2. Calponin33
- I. Introduction33
- II. Biochemical Properties of Calponin36
- III. Functional Properties of Calponin43
- IV. Structure–Function Relations57
- V. Calponin and Caldesmon58
- References59
- Chapter 3. Type III Cyclic Nucleotide Phosphodiesterases and Insulin Action63
- I. Introduction63
- II. Cyclic Nucleotide PDE Gene Families64
- III. Type III cGMP-Inhibited Cyclic Nucleotide Phosphodiesterases70
- References91
- Chapter 4. Mammalian Aminoacyl-tRNA Synthetases101
- I. Introduction101
- II. Classification of Mammalian Aminoacyl-tRNA Synthetases102
- III. General Structure of the RS Complex102
- IV. Dissociation and Organization of the Synthetase Complex105
- V. Primary Structures of Mammalian Synthetases107
- VI. Distinct Characteristics of N-Terminal Extensions in Mammalian Aminoacyl-tRNA Synthetases108
- VII. Functional Significance of Synthetase Complex111
- VIII. Aspartyl-tRNA Synthetase112
- IX. Arginyl-tRNA Synthetase118
- X. Lysyl-tRNA Synthetase119
- XI. GluPro-tRNA Synthetase120
- XII. Valyl-tRNA Synthetase Complex122
- XIII. Tryptophanyl-tRNA Synthetase124
- XIV. Seryl-tRNA Synthetase125
- XV. Threonyl-tRNA Synthetase126
- XVI. Correlation of the Classifications of Amino Acids and Mammalian Aminoacyl-tRNA Synthetases126
- XVII. Autoantibodies to Mammalian Synthetases127
- XVIII. Aminoacyl-tRNA Synthetases as Multifunctional Proteins128
- XIX. Organization of Synthetases and the Protein Biosynthetic Machinery129
- XX. Prospects129
- References131
- Chapter 5. Regulation of Interaction between Signaling Protein Chey and Flageller Motor during Bacte137
- I. Introduction137
- II. Proteins That Participate in CheY–Switch Interaction140
- III. Regulation of the CheY–Switch Interaction143
- IV. Concluding Remarks153
- References154
- Chapter 6. Chemical Biology of Nitric Oxide: Regulation and Protective and Toxic Mechanisms159
- I. Introduction159
- II. Chemical Aspects of Nitric Oxide161
- III. Biochemical Targets for Nitric Oxide167
- IV. Extracellular and Intracellular Metabolism of Nitric Oxide172
- V. Nitric Oxide and Oxidative Stress175
- VI. Conclusions: Direct versus Indirect Effects of Nitric Oxide on Biological Systems182
- References183
- Chapter 7. Nutritional and Hormonal Regulation of Glutathione Homeostasis189
- I. Introduction189
- II. Glutathione Synthesis and Interorgan Homeostasis191
- III. Regulation of Tissue Glutathione Concentration by Diet and Nutritional Status192
- IV. Regulation of Glutathione by Hormones195
- V. Glutathione in the Vicious Cycle of Disease, Infection, and Malnutrition200
- References204
- Chapter 8. Protein Folding and Association: In Vitro Studies for Self-Organization and Targeting in209
- I. Introduction209
- II. Hierarchies of Structure, Stability, and Folding212
- III. Mechanism of Folding and Association218
- IV. Cellular Aspects257
- V. Practical Aspects292
- VI. Conclusions297
- References300
- Index315
Praise for the Series:
"Timely...High standard of Writing...It is to be highly recommended."
--Quarterly Journal of Experimental Physiology
This informative publication brings together knowledge of various aspects of cellular regulation. Current Topics in Cellular Regulation reviews the progress being made in those specialized areas of study that have undergone substantial development. It also publishes provocative new theories and concepts and serves as a forum for the discussion of general principles.
Researchers in cellular regulation as well as biochemists, molecular and cell biologists, microbiologists, biophysicists, physiologists, nutritionists, and pathologists will find Current Topics in Cellular Regulation a useful source of up-to-date information.
* CONTENTS: Regulatory Features of Multicatalytic and 26S Proteases. Calponin. Type III Cyclic Nucelotide Phosphodiesterases and Insulin Action. Mammalian Aminoacyl-tRNA Synthetases. Regulation of Interaction between Signaling Protein CheY and Flagellar Motor during Bacterial Chemotaxis. The Chemical Biology of Nitric Oxide: Regulation and Protective and Toxic Mechanisms. Nutritional and Hormonal Regulation of Glutathione Homeostasis. Protein Folding and Association: In Vitro Studies for Self Organization and Targeting in the Cell.
"Timely...High standard of Writing...It is to be highly recommended."
--Quarterly Journal of Experimental Physiology
This informative publication brings together knowledge of various aspects of cellular regulation. Current Topics in Cellular Regulation reviews the progress being made in those specialized areas of study that have undergone substantial development. It also publishes provocative new theories and concepts and serves as a forum for the discussion of general principles.
Researchers in cellular regulation as well as biochemists, molecular and cell biologists, microbiologists, biophysicists, physiologists, nutritionists, and pathologists will find Current Topics in Cellular Regulation a useful source of up-to-date information.
* CONTENTS: Regulatory Features of Multicatalytic and 26S Proteases. Calponin. Type III Cyclic Nucelotide Phosphodiesterases and Insulin Action. Mammalian Aminoacyl-tRNA Synthetases. Regulation of Interaction between Signaling Protein CheY and Flagellar Motor during Bacterial Chemotaxis. The Chemical Biology of Nitric Oxide: Regulation and Protective and Toxic Mechanisms. Nutritional and Hormonal Regulation of Glutathione Homeostasis. Protein Folding and Association: In Vitro Studies for Self Organization and Targeting in the Cell.