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Table of contents
- Copyright Pageiv
- Contentsv
- Contributorsvii
- Prefaceix
- Chapter 1. Developmental Roles and Clinical Significance of Hedgehog Signaling1
- I. Introduction2
- II. Cement Gland5
- III. Central Nervous System5
- IV. Circulatory System13
- V. Face and Head15
- VI. Gonads16
- VII. Gut Development18
- VIII. Hair and Feather Morphogenesis23
- IX. Implantation26
- X. Kidney and Adrenal Gland27
- XI. Lateral Asymmetry27
- XII. Limb and Fin of Vertebrates32
- XIII. Lungs and Trachea43
- XIV. Mammary Gland46
- XV. Myogenesis46
- XVI. Neural Crest49
- XVII. Pancreas Development50
- XVIII. Peripheral Nervous System52
- XIX. Pituitary Gland53
- XX. Prostate Gland54
- XXI. Sclerotome, Cartilage, and Bone54
- XXII. Segments, Appendages, and Compartments of Drosophila61
- XXIII. Tongue and Taste67
- XXIV. Tooth68
- XXV. Visual System70
- XXVI. Human Congenital Malformations75
- XXVII. Cancer80
- References83
- Chapter 2. Genomic Imprinting: Could the Chromatin Structure Be the Driving Force?115
- I. Introduction115
- II. How Imprinting Was Discovered116
- III. Identification of Imprinted Genes118
- IV. Ambiguous Definition119
- V. Mechanism122
- VI. Unexplained Features of Imprinting127
- VII. Biological Significance: Toward a Paradigm Shift130
- References133
- Chapter 3. Ontogeny of Hematopoiesis: Examining the Emergence of Hematopoietic Cells in the Vertebra139
- I. Introduction140
- II. Mammalian Hematopoiesis142
- III. Avian Hematopoiesis147
- IV. Xenopus Hematopoiesis148
- V. Zebrafish Hematopoiesis151
- VI. Summary152
- References153
- Chapter 4. Patterning the Sea Urchin Embryo: Gene Regulatory Networks, Signaling Pathways, and Cellu159
- I. Introduction160
- II. Cell Fate Specification during the Premorphogenetic Phase of Sea Urchin Development167
- III. Interactions between Conditionally Specified Tissue Territories in Defining Borders and Coordin185
- IV. Outlook192
- References192
- Index199
- Contents of Previous Volumes207
Book details
- Vendor Elsevier S & T
- SKU 9780121531539
- ISBN-13 9780080490878
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Together with other volumes in this series, Volume 53 presents thoughtful and forward-looking articles on developmental biology and developmental medicine. The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development. This volume in particular will be essential reading for anyone interested in stem cells, signaling, medical implications of developmental determinants, hematopoeisis, axis specification, and molecular genetics of development.
Key Features
* Includes a landmark review on Hedgehog genes and their gene products in invertebrate and vertebrate development
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
Key Features
* Includes a landmark review on Hedgehog genes and their gene products in invertebrate and vertebrate development
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
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