Current Topics in Developmental Biology
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Table of contents
- Copyright Pageiv
- Contentsv
- Contributorsix
- Prefacexi
- Chapter 1. The Balbiani Body and Germ Cell Determinants: 150 Years Later1
- I. Introduction1
- II. Xenopus4
- III. Drosophila melanogaster and Other Insects12
- IV. Caenorhabditis elegans17
- V. Planarians18
- VI. Chaetognaths19
- VII. Ascidians20
- VIII. Urodeles21
- IX. Zebrafish and Other Teleosts21
- X. Birds24
- XI. Mouse and Other Mammals24
- XII. Similarities among Different Organisms25
- Acknowledgments29
- References29
- Chapter 2. Fetal–Maternal Interactions: Prenatal Psychobiological Precursors to Adaptive Infant De37
- I. Introduction37
- II. Early Experience and Postnatal Environments39
- III. Early Experience and Genetics41
- IV. Early Experience and Learning43
- V. Complexity Dissonance Theory of Early Experience and Development44
- VI. The Effects of Prenatal Experience: Establishing the Pacer Range45
- VII. Conclusion53
- References55
- Chapter 3. Paradoxical Role of Methyl-CpG-Binding Protein 2 in Rett Syndrome61
- I. Introduction to Rett Syndrome61
- II. CpG Methylation and the Role of MeCP2 in Chromatin Organization63
- III. The Paradoxes65
- IV. A Reexamination of the Role of MeCP2 in the Pathogenesis of Rett Syndrome77
- Acknowledgments81
- References81
- Chapter 4. Genetic Approaches to Analyzing Mitochondrial Outer Membrane Permeability87
- I. Introduction87
- II. VDAC and Saccharomyces cerevisiae89
- III. VDAC and Drosophila melanogaster90
- IV. VDAC and Mus musculus93
- V. Conclusions112
- References113
- Chapter 5. Mitochondrial Dynamics in Mammals119
- I. Introduction119
- II. The Central Molecular Players120
- III. Mitochondrial Dynamics in the Control of Mammalian Mitochondrial Morphology129
- IV. Mitochondrial Dynamics and Mitochondrial Function130
- V. Mitochondrial Dynamics and Human Disease133
- VI. Mitochondrial Dynamics in Vertebrate Development134
- VII. Mitochondrial Dynamics and Apoptosis136
- VIII. Perspectives and Future Challenges138
- References139
- Chapter 6. Histone Modifications in Corepressor Functions145
- I. Introduction145
- II. Histone Modifications and Regulatory Potential146
- III. Corepressors and Histone-Modifying Activities149
- IV. Tup1–Ssn6 Corepressor Complex: A Model for Corepressor Flexibility?153
- V. Summary and Future Questions157
- Acknowledgments158
- References158
- Chapter 7. Death by Abl: A Matter of Location165
- I. Introduction165
- II. Nucleocytoplasmic Shuttling of Abl168
- III. Cytoplasmic Function of Abl173
- IV. Nuclear Function of Abl175
- V. Nuclear Exclusion of BCR-ABL or Abl in Cancer Cells183
- VI. Conclusions and Future Prospects186
- References187
- Index193
- Contents of Previous Volumes201
In keeping with the tradition of excellence of past volumes of Current Topics in Developmental Biology, this volume provides a comprehensive survey of major issues at the forefront of modern developmental biology and developmental medicine. Astonishing discoveries are presented in seven thoughtful and forward-looking articles.
* The Balbiani body and germ cell determinants: 150 years later
* Fetal-maternal interactions: Prenatal psychobiological precursors to adaptive infant development
* The Paradoxical Role of Methyl-CpG-Binding Protein 2 (MeCP2) in Rett Syndrome
* Genetic Approaches to Analyzing Mitochondrial Outer Membrane Permeability
* Mitochondrial dynamics in mammals
* Histone Modifications in Corepressor Functions
* Death by Abl, A Matter of Location
Clinical and fundamental researchers, as well as students and other professionals, will find this series an indispensable guide to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.
* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
* The Balbiani body and germ cell determinants: 150 years later
* Fetal-maternal interactions: Prenatal psychobiological precursors to adaptive infant development
* The Paradoxical Role of Methyl-CpG-Binding Protein 2 (MeCP2) in Rett Syndrome
* Genetic Approaches to Analyzing Mitochondrial Outer Membrane Permeability
* Mitochondrial dynamics in mammals
* Histone Modifications in Corepressor Functions
* Death by Abl, A Matter of Location
Clinical and fundamental researchers, as well as students and other professionals, will find this series an indispensable guide to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.
* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage