Current Topics in Developmental Biology
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Table of contents
- Contentsv
- Contributorsix
- Prefacexi
- Chapter 1. Hepatic Oval Cells: Helping Redefine a Paradigm in Stem Cell Biology1
- I. Hepatic Stem Cells: Characterization and Localization2
- II. Hepatic Stem Cells: Origin and Function7
- III. Extrahepatic Stem Cells: A Paradigm Shift9
- IV. Controversies12
- V. Hypotheses/Mechanisms18
- VI. The Future21
- References22
- Chapter 2. Meiotic DNA Replication29
- I. Introduction30
- II. General Features of Meiotic S Phase32
- III. Initiation of Premeiotic S Phase33
- IV. meiS Phase Progression36
- V. Meiosis-Specific Replication Factors40
- VI. Fidelity of DNA Replication42
- VII. Role of Replication for Subsequent Meiotic Events43
- VIII. Block to Meiotic Rereplication49
- IX. Conclusions52
- Acknowledgments52
- References52
- Chapter 3. Pollen Tube Guidance: The Role of Adhesion and Chemotropic Molecules61
- I. Introduction61
- II. Adhesion and Chemotropism64
- III. Chemocyanin: A Chemotropic Peptide in the Lily Stigma69
- IV. Outlook75
- References76
- Chapter 4. The Biology and Diagnostic Applications of Fetal DNA and RNA in Maternal Plasma81
- I. Introduction82
- II. Biology of Circulating Fetal Nucleic Acids84
- III. Diagnostic Applications of Fetal DNA Analysis in Maternal Plasma88
- IV. Fetal RNA in Maternal Plasma: A New Avenue to Noninvasive Prenatal Diagnosis92
- V. Preanalytical and Technical Issues on Fetal Nucleic Acids Analysis from Maternal Plasma94
- VI. Fetal Nucleic Acids Analysis: The Way Forward101
- Acknowledgments102
- References102
- Chapter 5. Advances in Tissue Engineering113
- I. Background on Tissue Engineering113
- II. Role of Scaffolds in Tissue Engineering116
- III. Using Progenitor and Stem Cells in Tissue Engineering118
- IV. Vascularization of Engineered Tissue Constructs122
- V. Tissue Engineering as an In Vitro Model for Cell Differentiation and Organogenesis124
- References124
- Chapter 6. Directions in Cell Migration Along the Rostral Migratory Stream: The Pathway for Migratio135
- I. Introduction135
- II. The Nature of Migration in the Rostral Migratory Stream138
- III. PSA-N-CAM in Chain Migrations139
- IV. Other Mechanisms Mediating Migration142
- V. Mechanisms for Directional Navigation144
- VI. Regulation of Differentiation into Mature Neurons145
- VII. Summary148
- Acknowledgment148
- References148
- Chapter 7. Retinoids in Lung Development and Regeneration153
- I. Stages of Lung Development154
- II. What is Retinoic Acid (RA)160
- III. RA is Required for Budding of the Foregut Tube161
- IV. Branching Morphogenesis is Inhibited by RA164
- V. RA is Required during the End of the Foetal Period (Pseudoglandular, Canalicular, and Terminal Sa169
- VI. RA is Required for Postnatal Septation (Alveologenesis)172
- VII. RA Induces Alveolar Regeneration175
- VIII. Speculations of the Mode of Action of RA179
- IX. Clinical Implications and Future Possibilities180
- Acknowledgment181
- References181
- Chapter 8. Structural Organization and Functions of the Nucleus in Development, Aging, and Disease191
- I. Introduction192
- II. The Nuclear Envelope (NE) and Lamina193
- III. Protein Components of the NE195
- IV. Functions of Lamins197
- V. Lamins and the NE in Development201
- VI. Envelopathies and Laminopathies205
- VII. Disease Mechanisms211
- VIII. Conclusions216
- References217
- Index229
- Contents of Previous Volumes237
Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology.
This volume contains eight important contributions from leading minds in developmental biology.
* Hepatic Oval Cells: Helping Redefine a Paradigm in Stem Cell Biology
* Meiotic DNA Replication
* Pollen Tube Guidance: the Role of Adhesion and Chemotropic Molecules
* The biology and diagnostic applications of fetal DNA and RNA in maternal plasma
* Advances in Tissue Engineering
* Directions in cell migration along the rostral migratory stream: the pathway for migration in the brain
* Retinoids in Lung Development and Regeneration
* Structural Organization and Functions of the Nucleus in Development, Aging and Disease
* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
This volume contains eight important contributions from leading minds in developmental biology.
* Hepatic Oval Cells: Helping Redefine a Paradigm in Stem Cell Biology
* Meiotic DNA Replication
* Pollen Tube Guidance: the Role of Adhesion and Chemotropic Molecules
* The biology and diagnostic applications of fetal DNA and RNA in maternal plasma
* Advances in Tissue Engineering
* Directions in cell migration along the rostral migratory stream: the pathway for migration in the brain
* Retinoids in Lung Development and Regeneration
* Structural Organization and Functions of the Nucleus in Development, Aging and Disease
* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage