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Table of contents
- Copyright Pageiv
- Contentsv
- Contributorsix
- Prefacexi
- Chapter 1. A Role for Endogenous Electric Fields in Wound Healing1
- I. Introduction2
- II. Endogenous Electric Fields Measured near Wounds4
- III. Epithelial Cells Exhibiting Galvanotaxis7
- IV. How Do Motile Cells Sense and Respond to the Imposed Electric Field?11
- V. Can Imposed Electric Fields be used to Stimulate Wound Healing?14
- VI. Clinical Trials Using Electric Fields to Stimulate Wound Healing19
- VII. Summary20
- References21
- Chapter 2. The Role of Mitotic Checkpoint in Maintaining Genomic Stability27
- I. Introduction27
- II. The Kinetochore is a Complex Structure for Cell Division29
- III. The Mitotic Checkpoint31
- IV. Mutations in Mitotic Checkpoint Proteins and Tumorigenesis41
- V. Conclusions and Future Directions45
- Acknowledgments48
- References48
- Chapter 3. The Regulation of Oocyte Maturation53
- I. Concept of Oocyte Maturation54
- II. Life and Death of an Oocyte56
- III. Maturation Promoting Factor70
- IV. Initiation of Oocyte Maturation73
- V. Cytoplasmic Control of Maturation84
- VI. Concluding Remarks98
- Acknowledgments99
- References99
- Chapter 4. Stem Cells: A Promising Source of Pancreatic Islets for Transplantation in Type 1 Diabete111
- I. Introduction112
- II. Islet Transplantation: Success with Limitations113
- III. Alternative Sources of Transplantable Islets114
- IV. Differentiation of Embryonic Stem Cells into Insulin-producing Cells115
- V. Identification of the Elusive Pancreatic Stem Cell119
- VI. Existence of Nonpancreatic Islet Progenitor Cells126
- VII. Summary128
- References129
- Chapter 5. Differentiation Potential of Adipose Derived Adult Stem (ADAS) Cells137
- I. Introduction137
- II. Adipose Tissue„Physiology138
- III. Adipose Tissue„Pathology142
- IV. Adipose Derived Adult Stem (ADAS)144
- V. ADAS Cell Differentiation Potential and Potential Therapeutic Applications146
- VI. Functional Tissue Engineering Considerations151
- VII. Conclusions and Future Directions153
- Acknowledgments153
- References154
- Index161
- Contents of Previous Volumes167
- Color Plate SectionPlate 1
Book details
- Vendor Elsevier S & T
- SKU 9780121531584
- ISBN-13 9780080524665
- Author Schatten, Gerald P.
- Category Science
- Subject Developmental Biology
Do you have questions about this book?
Together with other volumes in this series, Volume 58 presents thoughtful and forward-looking articles on developmental biology and developmental medicine.
Reviews include:
* A role for endogenous electric fields in wound healing
* The role of mitotic checkpoint in maintaining genomic stability
* The regulation of oocyte maturation
* Stem cells: A promising source of pancreatic islets for transplantation in type 1 diabetes
* Differentiation potential of adipose derived adult stem (ASAS) cells
The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.
* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
Reviews include:
* A role for endogenous electric fields in wound healing
* The role of mitotic checkpoint in maintaining genomic stability
* The regulation of oocyte maturation
* Stem cells: A promising source of pancreatic islets for transplantation in type 1 diabetes
* Differentiation potential of adipose derived adult stem (ASAS) cells
The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.
* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage
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