Current Topics in Developmental Biology
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Table of contents
- Copyright Pageiv
- Contentsv
- Contributorsix
- Chapter 1. Patterning and Lineage Specification in the Amphibian Embryo1
- I. Introduction2
- II. Xenopus as a Model System for Studying Early Embryogenesis3
- III. Dorsal–Ventral Specification4
- IV. The Spemann Organizer22
- V. The Three Germ Layers35
- VI. Developmental Pathways and Tumorigenesis47
- VII. Perspectives48
- References49
- Chapter 2. Transcriptional Programs Regulating Vascular Smooth Muscle Cell Development and Different69
- I. Introduction69
- II. Embryology of the Vascular Smooth Muscle Cell Lineage(s)70
- III. Commitment to the Smooth Muscle Cell Lineage73
- IV. Transcriptional Control of Vascular Smooth Muscle Cell Differentiation74
- V. SRF: A Nuclear Sensor Regulating Growth and Differentiation76
- VI. Modulation of VSMC Phenotype78
- VII. Conclusions and Future Challenges80
- References82
- Chapter 3. Myofibroblasts: Molecular Crossdressers91
- I. Myofibroblasts: An Overview91
- II. Myofibroblast Origin and the Role of PDGF92
- III. Cytokines and Myofibroblast Phenotypes94
- IV. MuscleŽ Structural Protein Expression in Myofibroblasts95
- V. Mechanisms of Muscle-SpecificŽ Gene Regulation in Myofibroblasts97
- VI. Myofibroblast Contractility100
- VII. Myofibroblasts and the Cell Cycle101
- VIII. Perspectives104
- References104
- Chapter 4. Checkpoint and DNA-Repair Proteins Are Associated with the Cores of Mammalian Meiotic Chr109
- I. Introduction110
- II. Structural Characteristics of Meiotic Chromosomes during the Prophase of Meiosis I111
- III. Meiotic Checkpoint and Recombination Proteins Are Associated with the Cores of the Meiotic Chro117
- IV. Conclusions and Perspectives127
- References127
- Chapter 5. Cytoskeletal and Ca2+ Regulation of Hyphal Tip Growth and Initiation135
- I. Introduction: Characteristics of Fungal Growth136
- II. The Cytoskeleton and Apical Growth in Fungi137
- III. Calcium and Apical Growth in Fungi154
- IV. Conclusions170
- References170
- Chapter 6. Pattern Formation during C. elegans Vulval Induction189
- I. Introduction190
- II. Spatial Regulation of VPC Competence193
- III. Temporal Regulation of VPC Competence and Commitment196
- IV. Downstream Events of RAS Signaling203
- V. Negative Regulation of RAS Signaling206
- VI. Lateral Signaling210
- VII. Evolutionary Implications212
- VIII. Conclusions and Future Directions213
- References214
- Chapter 7. A Molecular Clock Involved in Somite Segmentation221
- I. Introduction222
- II. Models for Somite Formation224
- III. A Molecular Clock Linked to Somitogenesis225
- IV. Notch Signaling Pathway229
- V. Other Genes Implicated in Somitogenesis236
- VI. Conservation of the Segmentation Clock in Evolution242
- References243
- Index249
- Contents of Previous Volumes257
In the embryonic stage of a multicellular organism, precise arrangements of different cell types arise. These cell types eventually become the tissues and organs of the organism if it is an animal, for instance. Developmental biology is the study of this process in both plants and animals and covers the entire development stage of the organism.
Current Topics in Developmental Biology provides a comprehensive survey of the major topics in this rapidly advancing field. The volumes are valuable to researchers in animal and plant development as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. With over thirty years of publication, this series is the longest-running forum for contemporary issues in developmental biology.
Current Topics in Developmental Biology provides a comprehensive survey of the major topics in this rapidly advancing field. The volumes are valuable to researchers in animal and plant development as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. With over thirty years of publication, this series is the longest-running forum for contemporary issues in developmental biology.