Current Topics in Developmental Biology

Schatten, Gerald P.

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Table of contents
  • Copyright Pageiv
  • Contentsv
  • Contributorsvii
  • Chapter 1. The Dynamics of Chromosome Replication in Yeast1
  • I. Introduction1
  • II. Assays for Origin Activity2
  • III. Organization of the Genome for Replication11
  • IV. Assembly and Activation of the Initiation Complex17
  • V. The Temporal Program of Origin Activation38
  • VI. Monitoring the Replication Program49
  • VII. Concluding Thoughts59
  • References59
  • Chapter 2. Micromechanical Studies of Mitotic Chromosomes75
  • I. Introduction76
  • II. Architecture and Components of Eukaryote Chromosomes79
  • III. Stretching Elasticity of Chromosomes94
  • IV. Bending Elasticity of Chromosomes104
  • V. Viscoelasticity of Chromosomes112
  • VI. Combined Biochemical–Micromechanical Study of Mitotic Chromosomes116
  • VII. Conclusion125
  • References133
  • Chapter 3. Patterning of the Zebrafish Embyro by Nodal Signals143
  • I. Introduction143
  • II. Zebrafish Nodal Signals144
  • III. Nodal Signaling Pathway146
  • IV. Patterning the Mesoderm and Endoderm153
  • V. Role of Nodal in Patterning the Ventral Nervous System158
  • VI. Patterning the Left–Right Axis162
  • VII. Future Directions165
  • References165
  • Chapter 4. Folding Chromosomes in Bacteria: Examining the Role of Csp Proteins and Other Small Nucle173
  • I. Introduction173
  • II. Small Nucleic Acid-Binding Proteins Implicated in Chromosome Folding in Escherichia coli175
  • III. Csp Proteins in Escherichia coli180
  • IV. Relationships among Escherichia coli Csp Proteins189
  • V. Csp Proteins of Bacillus Subtilis190
  • VI. The Crystal Structures of CspA and Related Proteins191
  • VII. Distribution of Small DNA-Binding Proteins in Archaea and Bacteria197
  • VIII. Conclusions198
  • References200
  • Index203
  • Contents of Previous Volumes215
  • Color Plate SectionPlate1
Book details
  • Vendor Elsevier S & T
  • SKU 9780121531553
  • ISBN-13 9780080490892
  • Author Schatten, Gerald P.
  • Category Science
  • Subject Developmental Biology

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Together with other volumes in this series, Volume 55 presents thoughtful and forward-looking articles on developmental biology and developmental medicine. The exceptional reviews in this volume of Current Topics in Developmental Biology will be valuable to both clinical and fundamental researchers, as well as students and other professionals who want an introduction to current topics in cellular and molecular approaches to developmental biology and clinical problems of aberrant development.

* Series Editor Gerald Schatten is one of the leading minds in reproductive and developmental science
* Presents major issues and astonishing discoveries at the forefront of modern developmental biology and developmental medicine
* The longest-running forum for contemporary issues in developmental biology with over 30 years of coverage