Elsevier S & T

Dendritic Cells: Biology and Clinical Applications

Lotze, Michael T.; Thomson, Angus W.

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Table of contents
  • Cover
  • Dendritic Cellsiii
  • Copyright Pageiv
  • Contentsv
  • Contributorsix
  • Foreword to the Second Editionxv
  • Preface to the Second Editionxviii
  • Preface to the First Editionxxi
  • PART I: ORIGIN AND MOLECULAR BIOLOGY OF DENDRITIC CELLS1
  • Chapter 1. The Development of Dendritic Cells from Hematopoietic Precursors3
  • Chapter 2. Dendritic Cells in the Thymus13
  • Chapter 3. T-cell Activation and Polarization by Dendritic Cells21
  • Chapter 4. Follicular Dendritic Cells: Molecules Associated with Function29
  • Chapter 5. Langerhans Cells35
  • Chapter 6. Dendritic Cell-Related Immunoregulation: Signals and Mediators51
  • PART II: DENDRITIC CELL BIOLOGY75
  • Chapter 7. Isolation, Culture and Propagation of Dendritic Cells77
  • Chapter 8. Phenotypic Characterization of Dendritic Cells97
  • Chapter 9. Targeted Knockouts Affecting DCs119
  • Chapter 10. Mobilization, Migration, and Localization of Dendritic Cells131
  • Chapter 11. Regulation of Antigen Capture, MHC Biosynthesis and Degradation by Dendritic Cells151
  • Chapter 12. Development and Testing of Dendritic Cell Lines165
  • Chapter 13. Dendritic Cell-Derived Exosomes179
  • Chapter 14. Dendritic Cells as Recipients of Cytokine Signals187
  • Chapter 15. Dendritic Cells and Chemokines203
  • Chapter 16. Studies of Endocytosis213
  • Chapter 17. Imaging Dendritic Cells: a Primer231
  • PART III: DENDRITIC CELLS AND INTERACTION WITH OTHER CELLS243
  • Chapter 18. NK Cells245
  • Chapter 19. B cells255
  • Chapter 20. Cells of the Monocyte/Macrophage Lineage263
  • Chapter 21. Endothelium275
  • Chapter 22. Dendritic Cell/Dendritic Cell Interaction289
  • PART IV: DENDRITIC CELLS IN THE PERIPHERY299
  • Chapter 23. Dendritic Cells in the Context of Skin Immunity301
  • Chapter 24. Dendritic Cells in the Respiratory Tract315
  • Chapter 25. Intestinal Dendritic Cells325
  • Chapter 26. Dendritic Cells in the Liver, Kidney, Heart, and Pancreas337
  • Chapter 27. Dendritic Cells in the Spleen and Lymph Nodes357
  • Chapter 28. Dendritic Cells in the Central Nervous System371
  • Chapter 29. Dendritic Cells in the Eye389
  • Chapter 30. Dendritic Cells in the Reproductive Tract411
  • PART V: DENDRITIC CELLS IN DISEASE423
  • Chapter 31. The Identification of dendritic cells in cancer425
  • Chapter 32. Dendritic Cells in Rejection and Acceptance of Solid Organ Allografts439
  • Chapter 33. Dendritic Cells and Autoimmunity459
  • Chapter 34. Interaction of Dendritic Cells with Bacteria473
  • Chapter 35. Dendritic Cells During Infection with HIV-1 and SIV487
  • Chapter 36. Interactions of Viruses with Dendritric Cells505
  • Chapter 37. Dendritic Cells in Allergy523
  • Chapter 38. DCs in Wound Healing539
  • Chapter 39. Dendritic Cells in Atherosclerosis547
  • PART VI: DC-BASED THERAPIES559
  • Chapter 40. Clinical Trials of Dendritic Cells for Cancer561
  • Chapter 41. Dendritic Cell Therapies for HIV-1 Infection573
  • Chapter 42. Dendritic Cell Tolerogenicity and Prospects for Dendritic Cell-Based Therapy of Allograf587
  • Chapter 43. Genetic Engineering of Dendritic Cells609
  • Chapter 44. Phagocytosis of Apoptotic Cells627
  • Chapter 45. Dendritic Cells and the Biology of Parasitism645
  • Annotated References by Year651
  • Index771
  • Color Plates796
Book details
  • Vendor Elsevier S & T
  • SKU 9780124558519R180
  • ISBN-13 9780080491073
  • Author Lotze, Michael T.; Thomson, Angus W.
  • Edition 2nd
  • Category Medical
  • Subject Immunology

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Description eBook delivery & access Reviews
Dendritic Cells, 2nd Edition is the new edition of the extremely successful book published in 1998. With the volume of literature on dendritic cells doubling every year, it is almost impossible to keep up. This book provides the most up-to-date synthesis of the literature, written by the very best authors. It is essential reading for any scientist working in immunology, cell biology, infectious diseases, cancer, transplantation, genetic engineering, or the pharmaceutical/biotechnology industry.

* An entirely new section on DC biology is included in this edition. Also new to this edition are chapters on:
* Imaging
* Interaction of dendritic cells with viruses
* Dendritic cells and dendrikines, chemokines and the endothelium
* Molecules expressed in dendritic cells
* Role of dendritic cells in wound healing and atherosclerosis
* Delivery of apoptotic bodies
* Genetic engineering of dendritic cells
* Imaging
* Practical aspects of clinical protocol development