Elsevier S & T

Diuretic Agents: Clinical Physiology and Pharmacology

Seldin, Donald W.; Giebisch, Gerhard H.

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Table of contents
  • Cover
  • Contentsv
  • Contributorsix
  • Prefacexiii
  • Part I: A History of Diuretics1
  • Chapter I. A History of Diuretics3
  • Part II: Renal Electrolyte Transport and Its Regulation29
  • Chapter II. Renal Electrolyte Transport and Its Regulation31
  • Part III: Physiology of Diuretic Action73
  • Chapter IIIA. Site and Mechanism of Action of Diuretics75
  • Chapter IIIB. Special Diuretics113
  • Chapter IIIC. Renal Hemodynamic Effects of Diuretics135
  • Chapter IIID. Extrarenal Effects of Diuretics171
  • Part IV: Diuretic Use187
  • Chapter IVA. Diuretic Pharmacokinetics and Pharmacodynamics189
  • Chapter IVB1. Adaptation to Diuretic Drugs209
  • Chapter IVB2. Use of Diuretics in Chronic Renal Disease and Nephrotic Syndrome233
  • Chapter IVB3. Effect of Prostaglandin Inhibition on the Action of Diuretic Agents247
  • Chapter IVB4. Impairment of Diuretic Secretion259
  • Chapter IVB5. Albumin as an Adjunct to Diuretics for the Treatment of Edema271
  • Chapter IVC1. Intensive Diuretic Therapy: High Doses, Combinations, and Constant Infusions281
  • Chapter IVC2. Circulatory Support: Dopamine and Dopamine Agonists as Adjuncts to Diuretic Therapy301
  • Chapter IVC3. Interactions between ACE Inhibitors and Diuretics321
  • Chapter IVC4. Atrial Natriuretic Peptide335
  • Part V: Indications343
  • Chapter VA1. The Pathophysiology of Edema Formation345
  • Chapter VA2. Use of Diuretics for the Treatment of Heart Failure359
  • Chapter VA3. Diuretic Treatment of the Nephrotic Syndrome389
  • Chapter VA4. The Use of Diuretics in the Treatment of Ascites and Edema in Hepatic Cirrhosis407
  • Chapter VA5. Diuretics in Pregnancy425
  • Chapter VA6. Idiopathic Edema431
  • Chapter VB. Hypertension and Its Treatment: The Place of Diuretics437
  • Chapter VC1. Water and Electrolyte Derangements: Overhydration461
  • Chapter VC2. High Altitude Sickness471
  • Chapter VC3. Diuretics in the Treatment of Metabolic Alkaloids483
  • Chapter VC4. Use of Diuretics in Disorders of Calcium Metabolism495
  • Chapter VD. Indications for the Use of Diuretics in Patients with Renal Impairment513
  • Chapter VE. Toxic Agents: Drug Overdose, Poisons, Contrast Media531
  • Chapter VF. Diuretics and Glaucoma543
  • Chapter VG. Diuretics and Cerebral Edema549
  • Part VI: Diuretic Complications557
  • Chapter VIA. Sodium: Volume Depletion and Hyponatremia559
  • Chapter VIB. Potassium Disturbances Associated with the Use of Diuretics571
  • Chapter VIC. Acid–Base Disturbances Associated with the Use of Diuretics585
  • Chapter VID. The Effects of Diuretics on Calcium Metabolism: Physiologic and Clinical Effects595
  • Chapter VIE. The Effects of Diuretics on Magnesium Metabolism: Physiologic and Clinical Effects611
  • Chapter VIF. Metabolic Derangements Associated with Diuretic Use: Insulin Resistance, Dyslipidemia,621
  • Chapter VIG. Ototoxicity637
  • Chapter VIH. Allergic Interstitial Nephritis Due to Diuretic Agents643
  • Index649
Book details
  • Vendor Elsevier S & T
  • SKU 9780126356908
  • ISBN-13 9780080530468
  • Author Seldin, Donald W.; Giebisch, Gerhard H.
  • Category Medical
  • Subject Pharmacology

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The only comprehensive work to cover all aspects of diuretic agents, the book discusses the pharmacology and toxicology of diuretic agents as well as the physiological effects. Experts in the field present the principles and experimental approaches for the study of interactions between pharmacologic compounds in relation to specific target organs. Diuretic Agents contains information on the mechanisms of action and application of diuretics, and details FDA regulations and pharmaceutical industry guidelines.

Key Features
* Written by experts in the field
* Covers all aspects of diuretic agents
* Includes information on the mechanisms of action and application of diuretics