Gas Chromatography and Mass Spectrometry: A Practical Guide

Kitson, Fulton G.; Larsen, Barbara S.; McEwen, Charles N.

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Table of contents
  • Cover
  • Copyright Pageiv
  • Contentsvii
  • Acknowledgmentsxi
  • Part I: The Fundamentals of GC/MS1
  • Chapter 1. What Is GC/MS?3
  • Chapter 2. Interpretation of Mass Spectra25
  • Chapter 3. Quantitative GC/MS35
  • Part II: GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types43
  • Chapter 4. Acids45
  • Chapter 5. Alcohols55
  • Chapter 6. Aldehydes63
  • Chapter 7. Amides69
  • Chapter 8. Amines77
  • Chapter 9. Amino Acids87
  • Chapter 10. Common Contaminants95
  • Chapter 11. Drugs and Their Metabolites97
  • Chapter 12. Esters107
  • Chapter 13. Ethers117
  • Chapter 14. Fluorinated Compounds123
  • Chapter 15. Gases139
  • Chapter 16. Glycols141
  • Chapter 17. Halogenated Compounds (Other Than Fluorinated)145
  • Chapter 18. Hydrocarbons151
  • Chapter 19. Isocyanates157
  • Chapter 20. Ketones161
  • Chapter 21. Nitriles167
  • Chapter 22. Nitroaromatics173
  • Chapter 23. Nitrogen-Containing Heterocyclics181
  • Chapter 24. Nucleosides (TMS Derivatives)187
  • Chapter 25. Pesticides191
  • Chapter 26. Phenols201
  • Chapter 27. Phosphorus Compounds205
  • Chapter 28. Plasticizers and Other Polymer Additives (Including Phthalates)209
  • Chapter 29. Prostaglandins (MO-TMS Derivatives)213
  • Chapter 30. Solvents and Their Impurities217
  • Chapter 31. Steroids221
  • Chapter 32. Sugars (Monosaccharides)225
  • Chapter 33. Sulfur Compounds229
  • Part III: Ions for Determining Unknown Structures237
  • Part IV: Appendices325
  • Appendix 1. Definitions of Terms Related to Gas Chromatography327
  • Appendix 2. Tips for Gas Chromatography329
  • Appendix 3. Derivatives Found Useful in GC/MS335
  • Appendix 4. Cross-Index Chart for GC Phases343
  • Appendix 5. McReynolds' Constants345
  • Appendix 6. Simple GC Troubleshooting347
  • Appendix 7. Definitions of Terms Related to Mass Spectrometry351
  • Appendix 8. Tips and Troubleshooting for Mass Spectrometers355
  • Appendix 9. Atomic Masses and Isotope Abundances359
  • Appendix 10. Structurally Significant McLafferty Rearrangement Ions361
  • Appendix 11. Isotope Patterns for Chlorine and Bromine363
  • Appendix 12. Mixtures for Determining Mass Spectral Resolution365
  • Index369
Book details
  • Vendor Elsevier S & T
  • SKU 9780124833852
  • ISBN-13 9780080532325
  • Author Kitson, Fulton G.; Larsen, Barbara S.; McEwen, Charles N.
  • Category Science
  • Subject Analytic

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This guide provides, under one cover, a wealth of practical information designed to facilitate the effectiveness of the GC/MS user. Separation conditions for numerous compound types are provided along with derivatized and underivatized compounds. A section on how to interpret mass spectral data, an extensive correlation of ion masses and neutral losses with possible structures, and examples of mass spectra are provided to further aid structure determination. Also included are basic information on instrumentation, ionization methods, quantitation, tips on the operation of mass spectrometers, the best derivatization procedures for a variety of compound types, troubleshooting techniques, and a variety of other information found to be useful to the practicing user of GC/MS instrumentation. This guide would be immediately valuable to the novice as well as the experienced GC/MS user who may not have the breadth of experience covered in this book.

Key Features
* Condenses and organizes recent and essential information for new and experienced GC/MS users
* Comprehensively indexed and referenced
* Includes practical methods of analysis
* Serves as a text reference for short practical courses on the subject