Elsevier S & T

Handbook of Vertebrate Immunology

Pastoret, Paul-Pierre; Griebel, Philip; Bazin, Hervé; Govaerts, André

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Table of contents
  • Cover
  • CONTENTSv
  • List of Section Editorsxi
  • List of Contributorsxiii
  • Prefacexix
  • CHAPTER I. INTRODUCTION1
  • CHAPTER II. IMMUNOLOGY OF FISHES3
  • 1. Introduction3
  • 2. Lymphoid organs and their anatomical distribution3
  • 3. Leukocytes and their markers6
  • 4. Leukocyte traffic and associated molecules9
  • 5. Cytokines11
  • 6. T-cell receptor13
  • 7. Immunoglobulins15
  • 8. Major histocompatibility complex (MHC) antigens23
  • 9. Red blood cell antigens25
  • 10. Ontogeny of the immune system26
  • 11. Passive transfer of immunity30
  • 12. Nonspecific immunity31
  • 13. Complement system36
  • 14. Mucosal immunity39
  • 15. Acquired immunodeficiencies40
  • 16. Tumors of the immune system41
  • 17. Conclusions41
  • 18. References43
  • CHAPTER III. IMMUNOLOGY OF AMPHIBIANS63
  • 1. Introduction63
  • 2. Lymphoid organs and lymphocytes63
  • 3. Lymphocyte antigen-specific receptors65
  • 4. The major histocompatibility complex (MHC)67
  • 5. Immunobiology of T and B cells68
  • 6. Ontogeny of the immune response69
  • 7. Tumors of the immune system70
  • 8. Conclusion70
  • 9. References70
  • CHAPTER IV. AVIAN IMMUNOLOGY73
  • 1. Introduction73
  • 2. Lymphoid organs and their anatomical distribution73
  • 3. Leukocyte markers in the chicken81
  • 4. T-cell receptors87
  • 5. Cell surface and secreted immunoglobulins in B cell development89
  • 6. Major histocompatibility complex (MHC) antigens92
  • 7. Cytokines95
  • 8. Complement99
  • 9. Ontogeny of the immune system101
  • 10. Immunocompetence of the embryo and the newly-hatched chick104
  • 11. Mucosal gut immunity105
  • 12. Tumors of the immune system108
  • 13. Autoimmunity in avian model systems111
  • 14. Effect of viruses on immune functions113
  • 15. Concluding remarks113
  • 16. References117
  • CHAPTER V. IMMUNOLOGY OF THE RAT137
  • 1 Introduction137
  • 2. Lymphoid organs: their anatomical distribution and cell composition137
  • 3. Rat cluster of differentiation (CD) antigens142
  • 4. Leukocyte traffic and associated molecules142
  • 5 . Cytokines and their receptors150
  • 6. T-cell development150
  • 7. The T-cell receptor162
  • 8. B-cell development168
  • 9. Rat immunoglobulins171
  • 10. Rat Ig variable region genes173
  • 11. B lymphoid tumors and immunocytomas177
  • 12. The major histocompatibility complex179
  • 13. Nonspecific immunity183
  • 14. Components of the mucosal immune system187
  • 15. The complement system190
  • 16. Models of immunodeficiency in the rat192
  • 17. Autoimmunity194
  • 18. References198
  • CHAPTER VI. IMMUNOLOGY OF LAGOMORPHS223
  • 1. Introduction223
  • 2. Lymphoid organs, their anatomical distribution and ontogeny of the immune system223
  • 3. Rabbit leukocyte markers226
  • 4. Leukocyte traffic and associated molecules230
  • 5. Cytokines233
  • 6. T-cell receptor (TCR)233
  • 7. Immunoglobulins235
  • 8. MHC antigens238
  • 9. Rabbit blood groups242
  • 10. Passive transfer of immunity243
  • 11. Nonspecific immunity243
  • 12. Complement system243
  • 13. Mucosal immunity245
  • 14. Immunodeficiencies248
  • 15. Tumors of the immune system248
  • 16. Autoimmune diseases248
  • 17. Conclusions250
  • 18. References251
  • CHAPTER VII. IMMUNOLOGY OF THE DOG261
  • 1. Introduction261
  • 2. Lymphoid organs and their anatomical distribution261
  • 3. Leukocytes and their antigens263
  • 4. Leukocyte traffic and associated molecules264
  • 5. Cytokines267
  • 6. T-cell receptor268
  • 7. Immunoglobulins268
  • 8. Major histocompatibility complex (MHC) antigens268
  • 9. Red blood cell antigens270
  • 10. Ontogeny of the immune system271
  • 11. Passive transfer of immunity271
  • 12. Neonatal immune responses272
  • 13. Nonspecific immunity273
  • 14. Complement system274
  • 15. Mucosal immunity275
  • 16. Immunodeficiencies277
  • 17. Tumors of the immune system278
  • 18. Autoimmunity278
  • 19. Conclusions282
  • 20. References282
  • CHAPTER VIII. IMMUNOLOGY OF THE CAT289
  • 1. Introduction289
  • 2. Lymphoid organs and their anatomical position289
  • 3. Leukocyte differentiation antigens294
  • 4. Cytokines297
  • 5. The major histocompatibility complex301
  • 6. Red blood cell antigens303
  • 7. Immunoglobulins304
  • 8. Passive transfer of maternal immunity305
  • 9. Neonatal immune responses308
  • 10. Nonspecific immunity in the cat309
  • 11. The complement system311
  • 12. Ontogeny of the immune system313
  • 13. Mucosal immunity313
  • 14. Immunological diseases315
  • 15. Immunodeficiency diseases321
  • 16. Tumors of the immune system325
  • 17. Conclusions327
  • 18. References327
  • CHAPTER IX. IMMUNOLOGY OF MUSTELIDAE337
  • 1. Introduction337
  • 2. Badger337
  • 3. Ferret337
  • 4. River otter337
  • 5. Sea otter338
  • 6. Skunk338
  • 7. Mink338
  • 8. Conclusions340
  • 9. References340
  • CHAPTER X. IMMUNOLOGY OF HORSES AND DONKEYS343
  • 1. Introduction343
  • 2. Leukocytes and their antigens343
  • 3. Immunoglobulins347
  • 4. Cytokines350
  • 5. Major histocompatibility complex (MHC) antigens353
  • 6 . Innate immunity354
  • 7. Development of equine immunity355
  • 8. Disorders of the immune system356
  • 9. Tumors of the immune system359
  • 10. Reproductive immunology359
  • 11. Conclusions361
  • 12. References361
  • CHAPTER XI. IMMUNOLOGY OF THE PIG373
  • 1. Introduction373
  • 2. Lymphoid organs and their anatomical distribution373
  • 3. Leukocytes and their markers374
  • 4. Leukocyte traffic and associated molecules377
  • 5 . Cytokines and interferons379
  • 6. T-cell receptor383
  • 7. Immunoglobulins384
  • 8. Major histocompatibility complex (MHC) antigens387
  • 9. Red blood cell antigens389
  • 10. Ontogeny of the immune system394
  • 11. Passive transfer of immunity395
  • 12. Neonatal immune responses397
  • 13. Nonspecific immunity398
  • 14. Complement system400
  • 15. Mucosal immunity402
  • 16. Immunodeficiencies405
  • 17. Tumors of the immune system405
  • 18. Autoimmunity406
  • 19. Conclusions406
  • 20. References407
  • CHAPTER XII. IMMUNOLOGY OF CAMELS AND LLAMAS421
  • 1. Introduction421
  • 2. Lymphoid organs and their anatomical distribution422
  • 3. Leukocytes and their markers422
  • 4. Immunoglobulins423
  • 5. Phylogeny of the camelid immune system429
  • 6. Ontogeny of the immune system430
  • 7. Passive transfer of immunity430
  • 8. Blood groups432
  • 9. Nonspecific immunity432
  • 10. Complement system432
  • 11. Immunodeficiencies432
  • 12. Tumors of the immune system434
  • 13. Conclusions434
  • 14. Acknowledgements435
  • 15. References435
  • CHAPTER Xlll. IMMUNOLOGY OF CATTLE439
  • 1. Introduction439
  • 2. Lymphoid organs439
  • 3. The leukocytes and their markers444
  • 4. Cytokines447
  • 5. The T-cell receptor454
  • 6. Immunoglobulins456
  • 7. Major histocompatibility complex (MHC) antigens459
  • 8. Red blood cell antigens462
  • 9. Passive transfer of immunity464
  • 10. Nonspecific immunity466
  • 11. Complement system469
  • 12. References471
  • CHAPTER XIV. SHEEP IMMUNOLOGY AND GOAT PECULIARITIES485
  • 1. Introduction485
  • 2. Lymphoid organs and their anatomical distribution485
  • 3. Leukocytes and their markers489
  • 4. Leukocyte migration493
  • 5. Sheep cytokines496
  • 6. T-cell receptors500
  • 7. Immunoglobulins503
  • 8. Ovine major histocompatibility complex antigens (Ovar)505
  • 9. Sheep red blood cell antigens509
  • 10. Ontogeny of the immune system510
  • 11. Transmission of passive immunity in the sheep513
  • 12. The neonatal immune system515
  • 13. Innate immune mechnisms in the sheep518
  • 14. Complement522
  • 15. Mucosal immunity523
  • 16. Immunodeficiencies528
  • 17. Tumors of the immune system530
  • 18. Experimental investigation of autoimmunity in the sheep531
  • 19. Conclusions533
  • 20. References533
  • CHAPTER XV. IMMUNOLOGY OF THE BUFFALO555
  • 1. Introduction555
  • 2. Lymphoid organs555
  • 3. Leukocytes and their markers556
  • 4. Leukocyte traffic557
  • 5. Cytokines557
  • 6. T-cell receptor558
  • 7. Major histocompatibility complex (MHC) antigens558
  • 8. Immunoglobulins558
  • 9. Passive transfer of immunity559
  • 10. Neonatal immmunity560
  • 11. Nonspecific immunity560
  • 12. Complement560
  • 13. Immunomodulation560
  • 14. Tumors of the immune system561
  • 15. References561
  • CHAPTER XVI. THE MOUSE MODEL563
  • I. Introduction563
  • 2. The lymphoid organs563
  • 3. Immunoglobulins570
  • 4. Cellular immunology586
  • 5. Murine models of immunodeficiency589
  • 6. References594
  • CHAPTER XVll. THE SCID MOUSE MUTANT: DEFINITION AND POTENTIAL USE AS A MODEL FOR IMMUNE DISORDERS603
  • 1 . Introduction603
  • 2. The SCID mouse603
  • 3 . The SCID model of human immune responses604
  • 4. The SCID ‘leaky’ phenotype and new immune deficient murine strain607
  • 5 . SCID model of normal and neoplastic human haematopoiesis608
  • 6. Use of the SCID model without reconstitution610
  • 7. Acknowledgements611
  • 8. References611
  • CHAPTER XVlll. XENOTRANSPLANTATION619
  • 1. Introduction619
  • 2. Hyperacute and delayed discordant xenograft rejection620
  • 3. Human circulating xenoreactive natural antibodies620
  • 4. The xenoantigens623
  • 5. Complement activation623
  • 6. Endothelial cell activation624
  • 7. Tolerance and endothelial cell accommodation626
  • 8. Therapeutic approaches: future trends626
  • 9. Conclusions629
  • 10. References629
  • CHAPTER XIX. CONCLUSIONS635
  • GLOSSARY637
  • INDEX661
  • Color Plate Section674
Book details
  • Vendor Elsevier S & T
  • SKU 9780125464017
  • ISBN-13 9780080533766
  • Author Pastoret, Paul-Pierre; Griebel, Philip; Bazin, Hervé; Govaerts, André
  • Category Medical
  • Subject Immunology

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Description eBook delivery & access Reviews
This unique book provides a comprehensive and comparative guide to the immune systems of major vertebrate species, including domestic and wild animals of veterinary or medical interest, fish and amphibia. Data in this essential reference work has been compiled by world-renowned editors and an international group of authors. For each species, the information is presented in a structured 'user-friendly' format allowing easy cross reference and comparison between the various species.
This book will be considered the definitive reference work on vertebrate immunology and will be essential for scientists and professionals working in Immunology, Vaccinology or with Animal Models, for students of Veterinary or Human Medicine, Biology and researchers in Comparative Medicine and Physiology.

Each section, devoted to a major animal group covers:
* Lymphoid organs and their anatomical disposition
* Leukocytes and their markers
* Leukocyte traffic and associated molecules
* Cytokines
* T cell receptors
* Immunoglobulins
* MHC antigens
* Ontogeny of the immune system
* Passive transfer of immunity
* Neonatal immune responses
* Non-specific immunity
* Complement system
* Mucosal immunity
* Immunodeficiencies
* Tumours of the immune system
* Autoimmunity