Elsevier S & T

International Review Of Cytology: A Survey of Cell Biology

Jeon, Kwang W.

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Table of contents
  • Contentsv
  • Contributorsix
  • Chapter 1: Molecular Mechanism of Liver Development and Regeneration1
  • I. Introduction1
  • II. Specification of the Liver3
  • A. Signals for Liver Specification3
  • B. Segregation of the Liver and Pancreas4
  • III. Growth of the Fetal Liver5
  • A. Formation of the Liver Bud from the Liver Diverticulum5
  • B. Growth and Apoptosis of Hepatoblasts7
  • IV. Hepatocyte Differentiation12
  • A. Functional Differentiation12
  • B. Formation of Intercellular Junctions15
  • V. Cholangiocyte Differentiation17
  • A. Induction of Cholangiocytes18
  • B. Formation of Bile Ducts19
  • C. Abnormal Bile Duct Development in Mutant Animals22
  • VI. Liver Regeneration23
  • A. Proliferation of Hepatocytes23
  • B. Remodeling of Extracellular Matrix24
  • VII. Liver Stem and Progenitor Cells25
  • A. Progenitors in the Liver26
  • B. Hepatic Differentiation of Embryonic and Somatic Stem Cells29
  • VIII. Concluding Remarks31
  • Acknowledgment33
  • References33
  • Chapter 2: Molecular Basis of Vertebrate Endoderm Development49
  • I. Introduction49
  • II. Vertebrate Endoderm Development51
  • A. Molecular Pathway Controlling Endoderm Formation51
  • B. Endoderm Development in Xenopus55
  • C. Zebrafish Endoderm Development73
  • D. Endoderm Development in Mice83
  • III. Conserved Molecular Mechanisms92
  • A. Similarities and Differences Between Species92
  • B. Gene Regulatory Networks93
  • C. Separating Endoderm from Mesoderm94
  • IV. Translational Embryology: Making Endoderm from Stem Cells95
  • V. Summary and Future Prospects97
  • Acknowledgments98
  • References99
  • Chapter 3: YidC as an Essential and Multifunctional Component in Membrane Protein Assembly113
  • I. Introduction113
  • II. YidC Membrane Insertase114
  • A. Topology of the Protein and Its Domains114
  • B. Homologues of YidC115
  • C. Biosynthesis of YidC120
  • III. Functions of YidC121
  • A. Substrates of the YidC-Only Pathway121
  • B. Functional Regions of YidC122
  • C. YidC in Action123
  • D. Folding of Membrane Proteins and Assembly of Complexes by YidC128
  • IV. Eukaryotic YidC Homologues129
  • A. Mitochondrial Oxa Proteins130
  • B. Chloroplast Homologues131
  • C. Functional Substitution of YidC by Its Eukaryotic Counterparts133
  • V. Conclusions134
  • References134
  • Chapter 4: Mitotic Spindle Dynamics in Drosophila139
  • I. Introduction139
  • II. Mitosis in Drosophila140
  • A. Outline of Mitosis140
  • B. Mitotic Cells in Drosophila140
  • III. Molecular Mechanisms Underlying Mitosis143
  • A. Microtubule Dynamics143
  • B. Mitotic Motor Action148
  • IV. Mitotic Spindle Assembly and Function in Drosophila154
  • A. Spindle Mechanics and Dynamics154
  • B. Spindle Assembly Checkpoint160
  • C. Mathematical Models163
  • D. Genome-Wide Screens of Mitotic Components164
  • V. Concluding Remarks166
  • Acknowledgments167
  • References167
  • Chapter 5: Neurogenesis in the Fish Retina173
  • I. Introduction: The Fish Retina as a Model System for Retinal Neurogenesis173
  • II. Neurogenesis in the Embryonic Fish Retina177
  • A. Spatiotemporal Patterns177
  • B. Intrinsic Factors181
  • C. Extrinsic Factors188
  • D. Early Signaling Events Required for Later Neurogenesis195
  • III. Persistent Retinal Neurogenesis in the Fish Retina198
  • A. The Circumferential Germinal Zone199
  • B. The Rod Photoreceptor Lineage202
  • C. Life History-Related Retinal Plasticity204
  • IV. Injury-Induced Neurogenesis in the Fish Retina205
  • A. Injury Models and Spatiotemporal Patterns of Regeneration207
  • B. Stem Cells and Developmental Genetics of Regeneration210
  • C. Functional Recovery213
  • V. Conclusions214
  • Acknowledgments215
  • References215
  • Index225
Book details
  • Vendor Elsevier S & T
  • SKU 9780123741080
  • ISBN-13 9780080489247
  • Author Jeon, Kwang W.
  • Category Science
  • Subject Cell Biology

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International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. This volume features articles on Molecular mechanism of liver development and regeneration; Molecular basis of vertebrate endoderm development; YidC as an essential and multifunctional component in membrane protein assembly; Mitotic spindle dynamics in Drosophila; and Neurogenesis in the Fish Retina.