International Review Of Cytology: A Survey of Cell Biology

Jeon, Kwang W.

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Table of contents
  • Contentsv
  • Contributorsix
  • Chapter 1. Biosynthesis and Alternate Targeting of the Lysosomal Cysteine Protease Cathepsin L1
  • I. Introduction2
  • II. Biosynthesis of Procathepsin L3
  • III. Biosynthetic Pathways8
  • IV. Expression of Cathepsin L and Its Targeting20
  • V. Fate of Procathepsin L Targeted to Endosomes27
  • VI. Activity of Secreted Procathepsin L34
  • VII. Concluding Remarks38
  • References40
  • Chapter 2. Microtubule-Associated Proteins and Their Essential Roles During Mitosis53
  • I. Introduction53
  • II. Mitotic Apparatus67
  • III. MAPs Required for Cell Division: Identification and Properties74
  • IV. Organization of the Mitotic Spindle91
  • V. Microtubule–Kinetochore Attachment and Metaphase Chromosome Alignment97
  • VI. Chromosome Segregation109
  • VII. Mitotic Exit and Cytokinesis111
  • VIII. Concluding Remarks116
  • References118
  • Chapter 3. Molecular and Functional Analysis of the Dictyostelium Centrosome155
  • I. Introduction156
  • II. Molecular Analysis of Centrosome Composition161
  • III. Molecular and Functional Analysis of Centrosomal Proteins in Dictyostelium166
  • IV. Microtubule-Associated Proteins as Integral Parts of the Centrosome177
  • V. Conclusions and Perspectives192
  • References193
  • Chapter 4. Polytene Chromosomes: 70 Years of Genetic Research203
  • I. Introduction204
  • II. Organization of Polytene Chromosomes206
  • III. Dosage Compensation237
  • IV. Replication in Polytene Chromosomes240
  • V. Heterochromatins241
  • VI. Telomeres in Polytene Chromosomes250
  • VII. Conclusion253
  • References254
  • Chapter 5. Insect Basic Leucine Zipper Proteins and Their Role in Cyclic AMP-Dependent Regulation of277
  • I. Introduction278
  • II. Basic Leucine Zipper Proteins278
  • III. cAMP Response Element Binding (CREB) Proteins286
  • IV. Concluding Remarks299
  • References300
  • Index311
Book details
  • Vendor Elsevier S & T
  • SKU 9780123646453
  • ISBN-13 9780080495682
  • Author Jeon, Kwang W.
  • Category Science
  • Subject Cell Biology

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International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Articles in this volume address biosynthesis and alternate targeting of the lysosomal cysteine protesase cathepsin L; microtubule-associated proteins and their essential roles during mitosis; molecular and functional analysis of the dictyostelium centrosome; polytene chromosomes; and insect basic leucine zipper proteins and their role in cyclic AMP dependent regulation of gene expression.