Elsevier S & T

Introduction to Psychoneuroimmunology

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Table of contents
  • Cover
  • Contentsxi
  • Prefacevii
  • Acknowledgmentsix
  • Chapter 1. Introduction1
  • I. Aim and Organization1
  • II. Source5
  • Chapter 2. Historical Antecedents7
  • I. Introduction7
  • II. Health8
  • III. Social Organization, Health, and Healing9
  • IV. Early Ideas about Health and Disease10
  • V. Empirical Approaches to Health14
  • VI. Science and Health15
  • VII. Concluding Comments19
  • VIII. Sources20
  • Chapter 3. Immune System Basics23
  • I. Introduction23
  • II. Molecular Self/Nonself Discrimination24
  • III. Cell Types, Proteins, and Genes24
  • IV. Immune System Cell Types and Complement25
  • V. Immune Cell Functions and Inflammation28
  • VI. Human Leukocyte Antigen System31
  • VII. Antigen Presentation32
  • VIII. Natural Killer Cells34
  • IX. B Lymphocytes, Antibody Structure, and Diversity35
  • X. T Lymphocytes37
  • XI. Cytokines, Chemokines, and Cell Adhesion42
  • XII. Lymphoid Organs and Leukocyte Traffic46
  • XIII. Immune Activation/Deactivation and Memory49
  • XIV. Development of Immune Functions50
  • XV. Measures of Immune Function51
  • XVI. Concluding Comments53
  • XVII. Sources55
  • Chapter 4. Endocrine-Immune Modulation57
  • I. Introduction58
  • II. Endocrine System59
  • III. Cytokines, Hormones, and Their Receptors63
  • IV. Anterior Pituitary Hormones and Immune Function64
  • V. Posterior Pituitary Gland Hormones and Immune Function73
  • VI. Other Hormones and Immune Function74
  • VII. Thymus Gland76
  • VIII. Concluding Comments77
  • IX. Sources79
  • Chapter 5. Neuroimmune Modulation81
  • I. Introduction82
  • II. Peripheral Nervous System82
  • III. Peripheral Nervous System Innervation of Lymphoid Organs86
  • IV. Chemical Signaling in the Periphery87
  • V. Functional Effects of Peripheral Neuroimmune Interactions89
  • VI. Central Nervous System92
  • VII. Bidirectional Central Nervous System–Immune94
  • VIII. Learning and Immune Responses98
  • IX. Personality and Immune Function99
  • X. Concluding Comments101
  • XI. Sources102
  • Chapter 6. Stress, Contextual Change, and Disease103
  • I. Introduction103
  • II. Selye’s Concept of Stress103
  • III. Ranking Life Events as Stressful106
  • IV. Stress as Contextual Change108
  • V. Social Context109
  • VI. Other Life Forms109
  • VII. Nonliving Environment110
  • VIII. Individual as Context111
  • IX. Disease as Contextual Change113
  • X. Concluding Comments114
  • XI. Sources115
  • Chapter 7. Psychosocial Stress: Neuroendocrine and Immune Effects117
  • I. Introduction117
  • II. Psychosocial Stress118
  • III. Effects on Endocrine Activity119
  • IV. Effects on Autonomic and Peripheral Neural Activity122
  • V. Effects on the Central Nervous System123
  • VI. Effects on the Immune System123
  • VII. Neuroendocrine–Immune Pathways129
  • VIII. Concluding Comments129
  • IX. Sources131
  • Chapter 8. Infection, Allergy, and Psychosocial Stress133
  • I. Introduction134
  • II. Infectious Diseases134
  • III. Allergic Diseases143
  • IV. Concluding Comments149
  • V. Sources151
  • Chapter 9. Cancer, Autoimmunity, and Psychosocial Stress153
  • I. Introduction154
  • II. Cancer154
  • III. Autoimmune Diseases164
  • IV. Concluding Comments175
  • V. Sources177
  • Chapter 10. Immune Activity and Psychopathology179
  • I. Introduction180
  • II. Access to Brain by Pathogens181
  • III. Immune Activity within the Brain181
  • IV. Nervous System Infections and Behavior184
  • V. Autoimmunity, Malignancy, and Behavior190
  • VI. Sensing Peripheral Immune Activity191
  • VII. Sickness Behavior193
  • VIII. Behavioral Disorders that Resemble Sickness Behavior194
  • IX. Psychiatric Disorders with a Link to Infection196
  • X. Concluding Comments203
  • XI. Sources204
  • Chapter 11. Immune Function Enhancement207
  • I. Introduction207
  • II. Beliefs, Suggestion, and Expectations208
  • III. Social Engagement213
  • IV. Expression of Emotion213
  • V. Sleep and Relaxation214
  • VI. Exercise and Physical Activity215
  • VII. Nutrition217
  • VIII. Concluding Comments221
  • IX. Sources222
  • Chapter 12. Integration and Implications225
  • I. Introduction225
  • II. Synopsis225
  • III. Microenvironments and Complexity228
  • IV. Unnecessary and Insufficient228
  • V. Implications for Research229
  • VI. Implications for Health Care232
  • VII. Economic Considerations233
  • VIII. Concluding Comments233
  • IX. Sources234
  • Glossary235
  • Index261
Book details
  • Vendor Elsevier S & T
  • SKU 9780122034565
  • ISBN-13 9780080535043

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Psychoneuroimmunology investigates the relationships between behavior, psychosocial factors, the nervous, endocrine, and immune systems, and disease. Each system affects the others, enhancing and/or inhibiting processes elsewhere in the body. Research in this field has grown tremendously in recent years as science better understands the checks and balances of these interdisciplinary systems and processes. Introduction to Psychoneuroimmunology provides the first introductory text for this complex field.

Beginning with a discussion of immune system basics, Introduction to Psychoneuroimmunology explores endocrine-immune modulation, neuro-immune modulation, the relationship between stress, contextual change, and disease, as well as infection, allergy, immune activity and psychopathology, and immune function enhancement. This text provides a sound introduction to the field and will serve as a valuable overview to what is otherwise a complex interdisciplinary subject at the junction of molecular biology, genetics, the neurosciences, immunology, cell biology, endocrinology, pharmacology, biochemistry, and the behavioral sciences.

* Provides a wide coverage of topics
* Presents a concise treatment of topics
* Includes concluding comments after each chapter
* Includes definitions of technical terms