Laboratory Animal Anaesthesia

Flecknell, Paul

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Table of contents
  • Copyright Pageiv
  • Contentsv
  • Prefacevii
  • Preface to the 2nd editionix
  • Glossaryxi
  • List of Tablesxv
  • List of Figuresxvii
  • Acknowledgementsxix
  • Introductionxxi
  • Chapter 1. Pre-operative Care1
  • I. Anaesthetic equipment, anaesthetic drugs and personnel1
  • II. The animal3
  • Chapter 2. Pre-anaesthetic Medication7
  • I. Anticholinergic drugs8
  • II. Tranquillizers and sedatives9
  • III. Narcotic analgesics12
  • Chapter 3. Anaesthesia15
  • I. General anaesthesia15
  • II. Local and regional anaesthesia69
  • III. Selection of anaesthetic agents: scientific and welfare considerations70
  • Chapter 4. Anaesthetic Management75
  • I. Pre-operative preparations75
  • II. Monitoring anaesthesia76
  • III. Anaesthetic problems and emergencies88
  • Chapter 5. Special techniques103
  • I. Controlled ventilation103
  • II. Long-term anaesthesia110
  • III. Anaesthesia of pregnant animals122
  • IV. Anaesthesia of neonates124
  • Chapter 6. Post-operative Care127
  • I. The recovery room environment127
  • II. Problems during the recovery period129
  • III. Management of post-operative pain136
  • IV. Conclusions157
  • Chapter 7. Anaesthesia of common laboratory species159
  • I. Small rodents160
  • II. Rabbits182
  • III. Cats190
  • IV. Dogs196
  • V. Ferrets201
  • VI. Pigs202
  • VII. Sheep and goats209
  • VIII. Primates213
  • IX. Other species216
  • References225
  • APPENDICES239
  • Appendix 1. Recommended techniques and physiological data239
  • Appendix 2. Estimation of required quantities of volatile anaesthetic agents and anaesthetic gases245
  • Appendix 3. Examples of dilutions of anaesthetic mixtures for small rodents247
  • Appendix 4. Basic equipment for anaesthesia of laboratory animals251
  • Appendix 5. Anaesthetic drugs „ UK and USA generic names, trade names and manufacturers253
  • Appendix 6. Addresses of drug manufacturers and suppliers259
  • Appendix 7. Sources of anaesthetic apparatus and related equipment.265
  • Index269
Book details
  • Vendor Elsevier S & T
  • SKU 9780122603617
  • ISBN-13 9780080535326
  • Author Flecknell, Paul
  • Edition 2nd
  • Category Science
  • Subject Experiments & Projects

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The use of safe and effective anaesthetic techniques can have a major influence both on the welfare of laboratory animals and the quality of the research results obtained in using them. In times of justified public and scientific concerns over such issues, the need for clear and concise advise on good technique is of paramount importance.
However, much anaesthetic work in the laboratory is carried out by research workers and support staff who have not benefited from specialist veterinary training. This second edition of Paul Flecknell's invaluable guide gives just the sort of clear concise practical information such people need. It follows all the key stages from preoperative care thorough anesthesia itself to the post - anaesthetic recovery period.
Following these general sections, there are specific instructions on regimes for particular laboratory animals, with advice on recommended agents, dosages and special procedures of importance. Particular emphasis is placed on welfare, pain reduction and proper post - procedural care.
The Second Edition of this now standard guide adds the results of the latest research, most effective anesthetics and useful illustrations of procedures and equipment and broadens the original book's coverage to include notes on fish, amphibia, reptiles and birds.
It will prove an essential addition to the library of any laboratory where animals are used for research.