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Table of contents
- Table of Contentsv
- Contributor to Volume 368vii
- Prefaceix
- Volumes in Seriesxi
- Section I: Reminiscences on Methods1
- Chapter 1. Transformations in Structural Biology: Personal View3
- Chapter 2. Origins11
- Chapter 3. Personal X-ray Reflections21
- Section II: Crystals43
- Chapter 4. Robotics for Automated Crystal Formation and Analysis45
- Chapter 5. Use of Limited Proteolysis to Identify Protein Domains Suitable for Structural Analysis77
- Chapter 6. Solvent Entropy Effects in the Formation of Protein Solid Phases84
- Chapter 7. Controlling Biomolecular Crystallization by Understanding the Distinct Effects of PEGs an105
- Chapter 8. Counter-diffusion Methods for Macromolecular Crystallization130
- Chapter 9. Growth Sectors and Crystal Quality154
- Chapter 10. Molecular Mechanisms of Defect Formation170
- Chapter 11. Cryocooling of Macromolecular Crystals: Optimization Methods188
- Chapter 12. The Well-Tempered Protein Crystal:Annealing Macromolecular Crystals217
- Section III: Data237
- Chapter 13. What Can I Have As a Source of X-Ray Synchrotron Radiation? A Primer for Potential Users239
- Chapter 14. Protein Crystal Structure Analysis from High- Resolution X-Ray Powder-Diffraction Data254
- Chapter 15. Macromolecular Crystal Quality268
- Chapter 16. Protein Structures at Atomic Resolution288
- Author Index339
- Subject Index363
- Color Plates SectionColor Plete-1
Book details
- Vendor Elsevier S & T
- SKU 9780121822712
- ISBN-13 9780080497099
- Author Carter, Jr., Charles W.
- Category Science
- Subject Biochemistry
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Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding.
* Methodological methods in crystals
* Methodological methods data analysis
* Methodological methods in crystals
* Methodological methods data analysis
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