Origin and Evolution of Viruses
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Table of contents
- Origin and Evolution of Virusesiii
- Copyright Pageiv
- Contentsv
- List of Contributorsvii
- Prefaceix
- Chapter 1. Nature and Evolution of Early Replicons1
- Chapter 2. Virus Origins: Conjoined RNS Genomes as Precursors to DNA Genomes25
- Chapter 3. Viroids in Plants: Shadows and Footprints of a Primitive RNA37
- Chapter 4. Mutation, Competition and Selection as Measured with Small RNA Molecules65
- Chapter 5. The Fidelity of Cellular and Viral Polymerases and its Manipulation for Hypermutagenesis87
- Chapter 6. Drift and Conservatism in RNA Virus Evolution: Are They Adapting or Merely Changing?115
- Chapter 7. Viral Quasispecies and Fitness Variations141
- Chapter 8. The Retroid Agents: Disease, Function and Evolution163
- Chapter 9. Dynamics of HIV Pathogenesis and Treatment197
- Chapter 10. Interplay Between Experiment and Theory in Development of a Working Model for HIV-1 Popu225
- Chapter 11. Plant Virus Evolution: Past, Present and Future263
- Chapter 12. Genetics, Pathogenesis and Evolution of Picornaviruses287
- Chapter 13. The Impact of Rapid Evolution of the Hepatitis Viruses345
- Chapter 14. Antigenic Variation in Influenza Viruses377
- Chapter 15. DNA Virus Contribution to Host Evolution391
- Chapter 16. Parvovirus Variation and Evolution421
- Chapter 17. The Molecular Evolutionary History of the Herpesviruses441
- Chapter 18. African Swine Fever Virus: A Missing Link Between Poxviruses and Iridoviruses?467
- Index481
Are infectious diseases caused by novel entities, viruses that have rapidly evolved into more pathogenic forms, or viruses that have crossed species divides and become more virulent in their alternative host? These questions and how new diseases such as AIDS emerged have prompted renewed interest in the ways viruses originated and co-evolved with their hosts.
Origin and Evolution of Viruses presents a full and clear description of general viral concepts and specific viral systems, and provides an excellent foundation to our understanding of how viruses emerged.
This unique and comprehensive work is essential reading for all researchers in virology, molecular biology and related areas, as well as evolutionary biologists interested in phylogenetic approaches to molecular evolution. The reader is taken on an illumination journey--in time and concepts--from the first primitive replicons to their present-day complex viral counterparts.
Apart from the obvious interest, as humans are potential hosts for these viruses, there is also a great deal of academic interest in the evolutionary aspects of this simple group of organisms, since information can be gained about the origin of stains/species and evolutionary patterns that might be applicable to higher species.
The book addresses:
* Nature and evolution of early replicons
* DNA and RNA viruses in both plants and animals
* Viral origin, mutation, and survival
* Antigenic variation in influenza virus
* Interplay between host evolution and DNA virus evolution
* Emergence of viral-induced diseases, e.g. hepatitis, influenza and HIV
Origin and Evolution of Viruses presents a full and clear description of general viral concepts and specific viral systems, and provides an excellent foundation to our understanding of how viruses emerged.
This unique and comprehensive work is essential reading for all researchers in virology, molecular biology and related areas, as well as evolutionary biologists interested in phylogenetic approaches to molecular evolution. The reader is taken on an illumination journey--in time and concepts--from the first primitive replicons to their present-day complex viral counterparts.
Apart from the obvious interest, as humans are potential hosts for these viruses, there is also a great deal of academic interest in the evolutionary aspects of this simple group of organisms, since information can be gained about the origin of stains/species and evolutionary patterns that might be applicable to higher species.
The book addresses:
* Nature and evolution of early replicons
* DNA and RNA viruses in both plants and animals
* Viral origin, mutation, and survival
* Antigenic variation in influenza virus
* Interplay between host evolution and DNA virus evolution
* Emergence of viral-induced diseases, e.g. hepatitis, influenza and HIV