Principles of Cellular Engineering: Understanding the Biomolecular Interface
Regular price
49.250 KD
inc. VAT
Couldn't load pickup availability
Table of contents
- CONTENTSvii
- CONTRIBUTORSxi
- PREFACExiii
- PART I: CELL-SUBSTRATE ADHESION1
- Chapter 1. Traction Forces Exerted by Adherent Cells3
- Chapter 2. Control of Endothelial Cell Adhesion by Mechanotransmission from Cytoskeleton to Substrat25
- Chapter 3. Use of Hydrodynamic Shear Stress to Analyze Cell Adhesion51
- Chapter 4. Cellular Tensegrity Models and Cell–Substrate Interactions81
- PART II: PHYSICAL CHEMISTRY OF THE CELL SURFACE103
- Chapter 5. Bond Formation During Cell Compression105
- Chapter 6. Dynamics of the Neutrophil Surface During Emigration from Blood123
- Chapter 7. Glycocalyx Regulation of Cell Adhesion143
- PART III: ENGINEERED BIOMIMETIC SURFACES171
- Chapter 8. Atomistic Modeling of Protein Adsorption to Ceramic Biomaterials in Water: A First Step T173
- Chapter 9. Model Cell Membrane Surfaces for Measuring Receptor–Ligand Interactions195
- Chapter 10. A Flow Chamber for Capillary Networks: Leukocyte Adhesion in Capillary-Sized, Ligand-Coa213
- PART IV: CELL ADHESION TO SURFACES UNDER FLOW233
- Chapter 11. Adhesion of Flowing Neutrophils to Model Vessel Surfaces: Constraint and Regulation by t235
- Chapter 12. Hydrodynamic Interactions Between Cells on Reactive Surfaces255
- Chapter 13. Dynamics of Platelet Aggregation and Adhesion to Reactive Surfaces Under Flow267
- INDEX295
- Color Plate Section316
This comprehensive work discusses novel biomolecular surfaces that have been engineered to either control or measure cell function at the atomic, molecular, and cellular levels. Each chapter presents real results, concepts, and expert perspectives of how cells interact with biomolecular surfaces, with particular emphasis on interactions within complex mechanical environments such as in the cardiovascular system. In addition, the book provides detailed coverage of inflammation and cellular immune response as a useful model for how engineering concepts and tools may be effectively applied to complex systems in biomedicine.
-Accessible to biologists looking for new ways to model their results and engineers interested in biomedical applications
-Useful to researchers in biomaterials, inflammation, and vascular biology
-Excellent resource for graduate students as a textbook in cell & tissue engineering or cell mechanics courses
-Accessible to biologists looking for new ways to model their results and engineers interested in biomedical applications
-Useful to researchers in biomaterials, inflammation, and vascular biology
-Excellent resource for graduate students as a textbook in cell & tissue engineering or cell mechanics courses