Elsevier S & T

Principles of Gender-Specific Medicine

Legato, Marianne J.

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Table of contents

Cover
Copyright Pageiv
Contentsvii
Forewordxiii
Prefacexv
Contributorsxvii
Volume 11
SECTION 1: Gender and Development1
Chapter 1. The Role of Gender in Neonatology3
Chapter 2. Endocrinology and Growth in Children and Adolescents12
Chapter 3. Gender-Specific Pulmonary Disease25
Chapter 4. Gender-Specific Aspects of Pediatric Hematology and Oncology36
Chapter 5. Gender Differences in Neurologic Conditions of Children44
Chapter 6. Gender and Sports: Past, Present, and Future48
Chapter 7. Gender Differences in Child and Adolescent Behavior52
SECTION 2: Central Nervous System61
Chapter 8. Gender Differences in the Functional Organization of the Brain63
Chapter 9. Do Sex Steroid Hormones Contribute to Sexual Differentiation of the Human Brain?71
Chapter 10. Hormonal and Nonhormonal Mechanisms of Sexual Differentiation of the Brain84
Chapter 11. Neuroprotective Effects of Estrogen96
Chapter 12. Brain Trauma, Sex Hormones, Neuronal Survival, and Recovery of Function104
Chapter 13. Gender Differences in Epilepsy116
Chapter 14. Sex Hormones and Headache129
Chapter 15. Gender Differences in Psychiatric Disorders with a Focus on Estrogen137
Chapter 16. Gender Differences in Psychopharmacology145
Chapter 17. The Question of Psychosexual Neutrality at Birth155
Chapter 18. Treating Psychologic Disorders During Pregnancy and Lactation167
SECTION 3: Cardiology183
Chapter 19. Gender and the Heart: Sex-Specific Differences in Normal Myocardial Anatomy and Physiolo185
Chapter 20. Gender and Its Impact on Risk Factors for Cardiovascular Disease193
Chapter 21. Gender-Specific Aspects of the Experience of Coronary Artery Disease215
Chapter 22. Gender Differences in the Outcome of Acute Myocardial Infarction224
Chapter 23. Dyslipidemia Management in Women and Men: Exploring Potential Gender Differences234
Chapter 24. Impact of Gender on the Response to Cardioactive Drugs241
Chapter 25. Hormone Replacement Therapy and Cardioprotection255
Chapter 26. Gender Differences in the Role of Stress and Emotion in Cardiovascular Function and Dise263
Chapter 27. Importance of and Barriers to Including Women in Clinical Trials275
SECTION 4: Pulmonology283
Chapter 28. Asthma: The Need for Different Approaches by Sex and Gender285
Chapter 29. Sex, Gender, and Chronic Obstructive Pulmonary Disease299
Chapter 30. Gender-Specific Considerations in Interstitial Lung Disease309
Chapter 31. Gender-Specific Considerations in Pulmonary Hypertension317
Chapter 32. Venous Thromboembolism: Gender Effects and Gender-Specific Risk Factors for Women332
Chapter 33. The Influence of Gender on Cough Reflex Sensitivity347
Chapter 34. Obstructive Sleep Apnea: Why the Gender Bias?355
Chapter 35. Gender Differences in the Sepsis Syndrome: Clinical Evidence and Potential Mechanisms360
SECTION 5: Gastroenterology375
Chapter 36. Normal Physiology of the Gastrointestinal Tract and Gender Differences377
Chapter 37. Gender Differences in Esophageal Function397
Chapter 38. Sex-Specific Features of Diseases of the Stomach406
Chapter 39. Small Intestine and Colonic Diseases415
Chapter 40. Gender Considerations in Inflammatory Bowel Disease428
Chapter 41. Gender-Related Differences in Functional Bowel Disorders438
Chapter 42. Gallbladder and Biliary Diseases: More Common in Women, More Severe in Men446
Chapter 43. Effect of Gender on Pancreatic Disease454
Chapter 44. Gender-Specific Issues in Liver Diseases463
Chapter 45. Gender Difference in Gastrointestinal Endoscopy477
SECTION 6: Reproductive Biology491
Chapter 46. The Birth of Reproductive Biology 1889 to 1940: An Historical Perspective493
Chapter 47. Modern Contraception in Men and Women507
Chapter 48. Ambiguous Genitalia in the Newborn518
Chapter 49. A Practical Approach to Male Infertility538
Chapter 50. Female Infertility and Assisted Reproductive Technology550
Chapter 51. Chronic Pelvic Pain in Men and Women: Pathogenesis, Diagnosis, and Treatment565
Chapter 52. Male and Female Sexual Dysfunction: Epidemiology, Pathophysiology, Classifications, and573
Chapter 53. Lower Urogenital Tract Dysfunction in Women and Men586
Chapter 54. Colorectal Disease in Women and Men594
Chapter 55. Aging and the Lower Urogenital System602
Chapter 56. The Consequences of Intersex Conditions in Adult Life615
Volume 2627
SECTION 7: Oncology627
Chapter 57. Gender Differences in Hematologic Malignancies629
Chapter 58. Effects of Hormone Deprivation in Survivors of Breast and Prostate Cancer637
Chapter 59. The Difference Between Male and Female Breast Cancer648
Chapter 60. Difference in the Germ Cell Tumors of the Reproductive Tract in Men and Women658
Chapter 61. Gender and Gastrointestinal Malignancies: Incidence and Response to Treatment664
Chapter 62. Gender Influences on the Development and Progression of Brain Tumors671
Chapter 63. Gender Differences in Hereditary Cancer Syndromes: Risks, Management, and Testing for In682
Chapter 64. Cancer Screening693
SECTION 8: Nutrition703
Chapter 65. Energy Requirements of Men and Women705
Chapter 66. Anorexia, Bulimia, Disordered Eating and Obesity715
Chapter 67. The Influence of Gender Differences in Metabolism upon Nutritional Recommendations for A729
Chapter 68. Cardiovascular Disease, Genes, and Nutrition: Gender Matters737
Chapter 69. Insulin Resistance and Type 2 Diabetes Mellitus: Gender Differences and Similarities752
Chapter 70. The Role of Nutrition in the Modulation of Sex Steroids759
Chapter 71. Nutrition and Cancers of the Breast, Endometrium, and Ovary770
Chapter 72. Nutrition and the Etiology and Prevention of Prostate Cancer783
Chapter 73. Human Papillomavirus Infection in Men and Women: The Impact of Nutrition on Cervical Can796
Chapter 74. Nutritional Antioxidants, Vitamins, Cognition, and Neurodegenerative Disease813
SECTION 9: Drug Metabolism825
Chapter 75. Anticoagulants/Antithrombotic Therapy831
Chapter 76. Pain Medications: Differences Between the Sexes843
Chapter 77. Evaluation of Drugs in Women: Regulatory Perspective848
Chapter 78. Gender and Antidepressants860
Chapter 79. Consideration for the Use of Therapeutic Drugs During Pregnancy and the Perinatal Period869
Chapter 80. Weight Reduction Therapies: Anorectants, Thermogenics, and Lipolytics874
Chapter 81. Hormone Replacement Therapy: Looking Closely at Low Dose882
Chapter 82. Use of Oral Contraceptive for Contraception889
SECTION 10: Infectious Disease899
Chapter 83. Gender and Bacterial Infections901
Chapter 84. Gender-Specific Issues in Fungal Infections910
Chapter 85. Sex and Gender-Specific Issues in HIV Pathogenesis923
Chapter 86. Gender-Specific Issues in the Metabolic Complications of HIV Disease and Its Treatment931
Chapter 87. The Effect of Gender on the Epidemiology, Clinical Presentation, and Management of Tuber938
Chapter 88. Gender-Specific Issues in Non-HIV Viral Infections946
Chapter 89. Gender-Specific Issues in Parasitology956
Chapter 90. Sexually Transmitted Infections in Men and Women966
SECTION 11: Bone979
Chapter 91. Corticosteroid-Induced Osteoporosis: A Comprehensive Review981
Chapter 92. Anabolic Therapy of Osteoporosis in Women and in Men995
Chapter 93. Antiresorptive Therapies of Osteoporosis in Women and Men1010
Chapter 94. The Role of Androgens and Estrogens in the Male Skeleton1021
Chapter 95. The Clinical Application of Gender-Based Databases for the Diagnosis of Osteoporosis and1033
Chapter 96. Animal Models for Gender-Based Skeletal Differences1043
Chapter 97. Epidemiology of Osteoporosis and Fracture in Men and Women1052
Chapter 98. Gender and Sports Medicine in the Adult Athlete1060
SECTION 12: Immunology/Rheumatology1069
Chapter 99. Sexual Dimorphism and the Immune System1071
Chapter 100. Estrogen, Signal Transduction, and Systemic Lupus Erythematosus: Molecular Mechanisms1082
Chapter 101. Sex Hormone Metabolism, Immune Function, and the Effect of Sex Hormones on Various Rheu1093
Chapter 102. Pregnancy„Success or Failure: The Influence of Autoimmune Diseases1106
Chapter 103. Gender-Specific Issues in Organ Transplantation1116
Chapter 104. Prolactin in Autoimmune Disease1128
SECTION 13: Aging1139
Chapter 105. A History of Old Age in America1141
Chapter 106. Breast Diseases in Older Women and Men1154
Chapter 107. Care of the Older Woman: Practical Issues1163
Chapter 108. Cancer Management in Older Women1171
Chapter 109. The Evaluation and Treatment of Urinary Incontinence1186
Chapter 110. Effects of Aging on Gonadotropin/Ovarian and Growth Hormone/Ovarian Relationships in No1197
Chapter 111. The Principle Syndromes of Dementia1216
Chapter 112. Mechanisms Involved in Gender Differences in Alzheimer’s Disease: The Role of Leutein1234
SECTION 14: Future Areas to Expand1239
113. Gender Differences in Dermatology1241
Index1247
Color Plates-SectionPlate1

Book details

Vendor Elsevier S & T
SKU 9780124409057
ISBN-13 9780080492148
Author Legato, Marianne J.
Category Medical
Subject Internal Medicine

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Principles of Gender-Specific Medicine examines how normal human biology differs between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men, and as well conditions that predominantly occur in women. Among the subjects covered are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious diseases.

* Gathers important information in the field of gender-based biology and clinical medicine, proving that a patient's sex is increasingly important in preventing illness, making an accurate diagnosis, and choosing safe and effective treatment of disease
* Addresses gender-specific areas ranging from organ transplantation, gall bladder and biliary diseases, to the epidemiology of osteoporosis and fractures in men and women
* Many chapters present questions about future directions of investigations

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