Elsevier S & T

Quinones and Quinone Enzymes, Part A

Sies, Helmut; Packer, Lester

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Table of contents
  • Table of Contentsvii
  • Contributors to Volume 378xi
  • Prefacexv
  • Volumes in Seriesxvii
  • Section I: Coenzyme Q: Detection and Quinone Reductases1
  • Chapter 1. Investigation of Regulatory Mechanisms in Coenzyme Q Metabolism3
  • Chapter 2. Methods for Characterizing TPQ-Containing Proteins17
  • Chapter 3. Aldo-Keto Reductases and Formation of Polycyclic Aromatic Hydrocarbon o-Quinones31
  • Chapter 4. Redox Cycling of β-Lapachone and Structural Analogues in Microsomal and Cytosol Liver P67
  • Chapter 5. Quinone Chemistry and Melanogenesis88
  • Chapter 6. Quinoids Formed from Estrogens and Antiestrogens110
  • Chapter 7. Ubiquinone and Plastoquinone Metabolism in Plants124
  • Chapter 8. Extramitochondrial Reduction of Ubiquinone by Flavoenzymes131
  • Chapter 9. Tissue Bioavailability and Detection of Coenzyme Q138
  • Chapter 10. Coemzyme Q and Vitamin E Interactions146
  • Chapter 11. Preparation of Tritium-Labeled 3-Methyl-3-buten-1[3H]-yl Diphosphate (3H-Isopentenyl Dip152
  • Chapter 12. High-Performance Liquid Chromatography–EC Assay of Mitochondrial Coenzyme Q9, Coenzyme156
  • Chapter 13. Simultaneous Determination of Coenzyme Q10, Cholesterol, and Major Cholesterylesters in162
  • Chapter 14. Assay of Coenzyme Q10 in Plasma by a Single Dilution Step170
  • Section II: Plasma Membrane Quinone Reductases177
  • Chapter 15. Quinone Oxidoreductases of the Plasma Membrane179
  • Chapter 16. Regulation of Ceramide Signaling by Plasma Membrane Coenzyme Q Reductases200
  • Chapter 17. Stabilization of Extracellular Ascorbate Mediated by Coenzyme Q Transmembrane Electron T207
  • Section III: Quinones, Cellular Signaling, and Modulation of Gene Expression219
  • Chapter 18. Regulation of Antioxidant Response Element–Dependent Induction of Detoxifying Enzyme S221
  • Chapter 19. Antioxidant Responsive Element Activation by Quinones: Antioxidant Responsive Element Ta238
  • Chapter 20. Signaling Effects of Menadione: From Tyrosine Phosphatase Inactivation to Connexin Phosp258
  • Chapter 21. Unique Function of the Nrf2–Keap1 Pathway in the Inducible Expression of Antioxidant a273
  • Chapter 22. Role of Protein Phosphorylation in the Regulation of NF-E2–Related Factor 2 Activity286
  • Chapter 23. Analysis of Transcription Factor Remodeling in Phase II Gene Expression with Curcumin302
  • Chapter 24. Quinones and Glutathione Metabolism319
  • Chapter 25. Doxorubicin Cardiotoxicity and the Control of Iron Metabolism: Quinone-Dependent and Ind340
  • Chapter 26. Oxidant-Induced Iron Signaling in Doxorubicin-Mediated Apoptosis362
  • Author Index383
  • Subject Index411
Book details
  • Vendor Elsevier S & T
  • SKU 9780121827823
  • ISBN-13 9780080497167
  • Author Sies, Helmut; Packer, Lester
  • Category Science
  • Subject Research & Methodology

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Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers the role of quinines enzymes in cellular signalling and modulation of gene expression.

*Coenzyme Q: Detection and Quinone Reductases
*Plasma Membrane Quinone Reductases
*Quinones, Cellular Signaling, and Modulation of Gene Expression