Elsevier S & T

Regenerative Biology and Medicine

Stocum, David L.

In stock
No reviews
37.000 KD inc. VAT
License
Table of contents
  • Cover
  • Title pageiii
  • Copyright pageiv
  • Table of Contentsv
  • Prefaceix
  • Chapter 1: An Overview of Regenerative Biology and Medicine1
  • Introduction1
  • A Brief History of Regenerative Biology and Medicine2
  • The Biology of Regeneration4
  • Strategies of Regenerative Medicine11
  • Summary17
  • References18
  • Chapter 2: Repair of Skin Wounds by Fibrosis21
  • Introduction21
  • Structure of Adult Mammalian Skin21
  • The Effect of Wound Type and Extent on Dermal Repair23
  • Phases of Repair in Excisional Wounds23
  • Molecular Comparison of Wounded vs. Unwounded Skin31
  • Fetal Skin Heals Without Scarring32
  • Summary35
  • References36
  • Chapter 3: Regeneration of Epidermal Tissues41
  • Introduction41
  • Regeneration of Epidermis and Hair41
  • Regeneration of Nails47
  • Regeneration of Dental Tissues48
  • Regeneration of the Lens50
  • Regeneration of the Cornea56
  • Summary57
  • References58
  • Chapter 4: Regenerative Medicine of Skin, Hair and Dental Tissues63
  • Introduction63
  • Repair of Skin63
  • Repair of Teeth and Peridontium76
  • Corneal Regeneration78
  • Summary82
  • References83
  • Chapter 5: Regeneration of Neural Tissues89
  • Introduction89
  • Axon Regeneration89
  • Maintenance Regeneration of Neurons in the Mammalian CNS99
  • Injury-Induced CNS Regeneration103
  • Summary115
  • References117
  • Chapter 6: Regenerative Medicine of Neural Tissues125
  • Introduction125
  • Therapies for Injured Peripheral Nerve125
  • Therapies for Injured Spinal Cord127
  • Therapies for Neurodegenerative Diseases140
  • Summary156
  • References158
  • Chapter 7: Regeneration of Digestive, Respiratory and Urogenital Tissues167
  • Introduction167
  • Intestinal Epithelium167
  • Liver170
  • Pancreas177
  • Alveolar Epithelium of the Lung181
  • Kidney and Urinary System183
  • Gonads188
  • Prostate Tissue188
  • Summary189
  • References190
  • Chapter 8: Regenerative Medicine of Digestive, Respiratory and Urinary Tissues197
  • Introduction197
  • Regenerative Therapies for the Liver197
  • Regenerative Therapies for the Pancreas201
  • Regenerative Therapies for the Esophagus and Intestine207
  • Regenerative Therapies for the Respiratory System209
  • Regenerative Therapies for the Urinary System210
  • Summary214
  • References216
  • Chapter 9: Regeneration of Musculoskeletal Tissues221
  • Introduction221
  • Regeneration of Skeletal Muscle221
  • Regeneration of Bone229
  • Repair of Articular Cartilage239
  • Repair of Tendon and Ligament241
  • Summary242
  • References244
  • Chapter 10: Regenerative Medicine of Musculoskeletal Tissues251
  • Introduction251
  • Regenerative Therapies for Muscle251
  • Regenerative Therapies for Meniscus and Articular Cartilage254
  • Regenerative Therapies for Bone262
  • Regenerative Therapies for Tendon and Ligament272
  • Summary274
  • References276
  • Chapter 11: Regeneration of Hematopoietic and Cardiovascular Tissues283
  • Introduction283
  • Regeneration of Hematopoietic Cells283
  • Regeneration of Blood Vessels287
  • Regeneration of Cardiac Muscle292
  • Summary299
  • References300
  • Chapter 12: Regenerative Medicine of Hematopoietic and Cardiovascular Tissues305
  • Introduction305
  • Therapies for Hematopoietic Disorders305
  • Therapies for Blood Vessel Regeneration312
  • Therapies for Protection and Regeneration of the Infarcted Myocardium317
  • Summary328
  • References329
  • Chapter 13: Regenerative Medicine: Developmental Plasticity of Adult Stem Cells337
  • Introduction337
  • Assays to Test Developmental Plasticity337
  • Experimental Results338
  • Many Reports of Lineage Conversion are Due to Fusion With Host Cells349
  • Adult Stem Cell Pluripotency: Fact or Fiction?350
  • Effects of Aging on Number and Developmental Status of Regeneration-Competent Cells351
  • Summary356
  • References358
  • Chapter 14: Regeneration of Appendages363
  • Introduction363
  • Amphibian Limb Regeneration363
  • Regeneration of Amphibian Jaws385
  • Appendage Regeneration in Mammals386
  • Summary395
  • References396
  • Chapter 15: Research Issues in Regenerative Medicine405
  • Introduction405
  • Biological Issues and Challenges.406
  • Bioethical Issues and Challenges420
  • Concluding Remarks425
  • Summary426
  • References427
  • Index433
Book details
  • Vendor Elsevier S & T
  • SKU 9780123693716
  • ISBN-13 9780080493022
  • Author Stocum, David L.
  • Category Science
  • Subject Biotechnology

Do you have questions about this book?

Ask an expert!

Description eBook delivery & access Reviews
The purpose of the book is to bring together in one place the different facets of regenerative biology and medicine while providing the reader with an overview of the basic and clinically-oriented research that is being done. Not only does the content cover a plethora tissues and systems, it also includes information about the developmental plasticity of adult stem cells and the regeneration of appendages.

As part of its balanced presentation, Regenerative Biology and Medicine does address the biological/bioethical issues and challanges involved in the new and exciting field of regenerative biology and medicine.

*Tissues covered include skin, hair, teeth, cornea, and central neural types
*Systems presented are digestive, respiratory, urogenital, musculoskeletal, and cardiovascular
*Includes amphibians as powerful research models
*Discusses appendage regeneration in amphibians and mammals