Elsevier S & T

Regulators of G Protein Signalling, Part B

Siderovski, David

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Table of contents
  • Table of Contentsv
  • Contributors to Volume 390ix
  • Prefacexiii
  • Volumes in Seriesxvii
  • Section I: The RGS Protein Superfamily1
  • Subsection A: RZ Subfamily3
  • Chapter 1. Evaluating Chick Ga-Interacting Protein Selectivity3
  • Chapter 2. Analyses of Ga-Interacting Protein and Activator of G-Protein-Signaling-3 Functions in Ma17
  • Chapter 3. Analysis of RGSZ1 Protein Interaction with Gai Subunits31
  • Chapter 4. Analysis of the Regulation of Microtubule Dynamics by Interaction of RGSZ1 (RGS20) with t53
  • Subsection B: R4 Subfamily65
  • Chapter 5. RGS2-Mediated Regulation of Gqa65
  • Chapter 6. Analysis of the Interaction between RGS2 and Adenylyl Cyclase83
  • Chapter 7. Assays of RGS3 Activation and Modulation99
  • Chapter 8. Analysis of PDZ-RGS3 Function in Ephrin-B Reverse Signaling120
  • Chapter 9. Biochemical and Electrophysiological Analyses of RGS8 Function129
  • Subsection C: R7 Subfamily149
  • Chapter 10. Biochemical Purification and Functional Analysis of Complexes between the G-Protein Subu149
  • Chapter 11. Purification and In Vitro Functional Analysis of R7 Subfamily RGS Proteins in Complex wi163
  • Chapter 12. Characterization of R9AP, a Membrane Anchor for the Photoreceptor GTPase- Accelerating P178
  • Chapter 13. Kinetic Approaches to Study the Function of RGS9 Isoforms196
  • Chapter 14. Assays of Nuclear Localization of R7/GB5 Complexes210
  • Subsection D: R12 Subfamily224
  • Chapter 15. Mapping of RGS12-Cav2.2 Channel Interaction224
  • Chapter 16. Analysis of Interactions between Regulator of G-Protein Signaling-14 and Microtubules240
  • Subsection E: RhoGEF Subfamily259
  • Chapter 17. Modular Architecture and Novel Protein–Protein Interactions Regulating the RGS-Contain259
  • Chapter 18. Regulation of RGS-RhoGEFs by Ga12 and Ga13 Proteins285
  • Subsection F: GRK Subfamily295
  • Chapter 19. Analysis of G-Protein-Coupled Receptor Kinase RGS Homology Domains295
  • Chapter 20. Characterization of GRK2 RH Domain-Dependent Regulation of GPCR Coupling to Heterotrimer310
  • Chapter 21. Analysis of Differential Modulatory Activities of GRK2 and GRK4 on Gaq-Coupled Receptor337
  • Subsection G: Other RGS Proteins354
  • Chapter 22. Identification and Functional Analysis of Dual- Specific A Kinase-Anchoring Protein-2354
  • Section II: Other Heterotrimeric G-Protein Signaling Regulators375
  • Subsection A: Activators377
  • Chapter 23. Purification and Functional Analysis of Ric- 8A: A Guanine Nucleotide Exchange Factor fo377
  • Chapter 24.Tubulin as a Regulator of G-Protein Signaling389
  • Chapter 25. Nucleoside Diphosphate Kinase–Mediated Activation of Heterotrimeric G Proteins403
  • Subsection B: Inhibitors419
  • Chapter 26. Purification and In Vitro Functional Analyses of RGS12 and RGS14 GoLoco Motif Peptides419
  • Chapter 27. GoLoco Motif Peptides as Probes of G a Subunit Specificity in Coupling of G-Protein-Coup437
  • Subsection C: Other Modulators451
  • Chapter 28. Experimental Systems for Studying the Role of G-Protein-Coupled Receptors in Receptor Ty451
  • Chapter 29. Identification and Biochemical Analysis of GRIN1 and GRIN2475
  • Author Index485
  • Subject Index505
Book details
  • Vendor Elsevier S & T
  • SKU 9780121827953
  • ISBN-13 9780080497273
  • Author Siderovski, David
  • Category Science
  • Subject Biochemistry

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This volume continues the in-depth treatment of the topic and covers the RSG protein superfamily including RZ, R4, R7, R12, RhoGEF, and GRK, as well as other heterotrimeric G-protein signaling regulators.

Table of Contents
-RZ Subfamily
-R4 Subfamily
-R7 Subfamily
-R12 Subfamily
-RhoGEF Subfamily
-GRK Subfamily
-Other RGS proteins
-Activators
-Inhibitors
-Other Modulators