Stem Cells

Potten, C.

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Table of contents
  • Cover
  • Contentsv
  • Contributorsvii
  • Prefacexi
  • Chapter 1. Stem cells and cellular pedigrees – a conceptual introduction1
  • Chapter 2. Stem cells and founder zones in plants, particularly their roots29
  • Chapter 3. The stem cell concept applied to shoot meristems of higher plants59
  • Chapter 4. Skeletal muscle stem cells: function and potential role in therapy75
  • Chapter 5. Cell progenitors in the neural crest99
  • Chapter 6. Phenotypic diversity and lineage relationships in vascular endothelial cells119
  • Chapter 7. Mammary stem cells in normal development and cancer147
  • Chapter 8. Liver stem cells233
  • Chapter 9. Regulation of proliferation and differentiation of stem cells in the male germ line283
  • Chapter 10. Stem cell repertoire in the intestine315
  • Chapter 11. Keratinocyte stem cells of cornea, skin and hair follicles331
  • Chapter 12. Tumour stem cells363
  • Chapter 13. Biology of the haemopoietic stem cell401
  • Chapter 14. Growth factors and the regulation of haemopoietic stem cells423
  • Chapter 15. Haemopoietic stem cells for gene therapy447
  • Index463
  • Color Plates SectionColor Plat
Book details
  • Vendor Elsevier S & T
  • SKU 9780125634557
  • ISBN-13 9780080541761
  • Author Potten, C.
  • Category Medical
  • Subject Oncology

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Stem cells are relatively undifferentiated cells which are the permanent lineage ancestor cells of tissues. Newly developed molecular biological techniques and probes have made possible dramatic advances in our ability to study the lineage development of stem cells. A major impetus to develop these techniques has been to identify specific stem cells for gene therapy purposes. The role that stem cells play in the development of cancer is also an important area. This book provides up-to-date reviews on a wide variety of stem cell systems by world experts. Chapters range from descriptions of the current knowledge of the biology of stem cells, to current molecular biological approaches and clinical implications. Oncologists and cell biologists will find this book of particular interest. It will also be usefule to radiobiologist, biotechnologists, and gene therapists.

Key Features
* Provides reviews of stem cell systems by world experts
* Covers stem cell biology in plants, invertebrates, and mammals
* Presents clinical implications of stem cell differentiation