Elsevier S & T

The Antiphospholipid Syndrome II: Autoimmune Thrombosis

Cervera, R.; Piette, J.C.; Shoenfeld, Yehuda

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Table of contents
  • Cover
  • Contentsxv
  • Prefacev
  • Editor biographyvii
  • List of Contributorsxi
  • Part I: History and Epidemiology of the Antiphospholipid Syndrome (Editor: Ronald A. Asherson)1
  • Chapter 1. Milestones in the Antiphospholipid Syndrome3
  • Chapter 2. Classification and Epidemiology of the Antiphospholipid Syndrome11
  • Part II: Immunology and Pathophysiology of the Antiphospholipid Syndrome (Editor: Yehuda Shoenfeld)21
  • Chapter 3. Lupus Anticoagulant: Detection, Standardization and Heterogeneity23
  • Chapter 4. Antibodies to Cardiolipin and other Phospholipids29
  • Chapter 5. β2-Glycoprotein I and anti-β2-Glycoprotein I Antibodies45
  • Chapter 6. Anti-Prothrombin Antibodies59
  • Chapter 7. The Annexins: A Target of Antiphospholipid Antibodies71
  • Chapter 8. Antiphospholipid/Endothelial Cell Interaction in the Pathogenesis of the Antiphospholipid79
  • Chapter 9. Tissue Factor, Protein C pathway and other Hemostasis Abnormalities in the Pathogenesis o91
  • Chapter 10. Systemic Involvement in the Antiphospholipid Syndrome: Lessons from Animal Models101
  • Chapter 11. Cytokines, Th1/Th2 and Adhesion Molecules in the Antiphospholipid Syndrome107
  • Chapter 12. Lessons from Monoclonal Antiphospholipid Antibodies113
  • Chapter 13. Immunogenetics of the Antiphospholipid Syndrome119
  • Chapter 14. Pathology of the Antiphospholipid Syndrome131
  • Chapter 15. Antiphospholipid Antibodies in Human and Murine Atherogenesis137
  • Part III: Clinical Features in the Antiphospholipid Syndrome (Editor: Ricard Cervera)143
  • Chapter 16. Thrombotic Manifestations in the Antiphospholipid Syndrome145
  • Chapter 17. Neurologic Manifestations in the Antiphospholipid Syndrome155
  • Chapter 18. Cardiac and Pulmonary Manifestations in the Antiphospholipid Syndrome169
  • Chapter 19. Renal, Hepatic and other Intra-abdominal Manifestations in the Antiphospholipid Syndrome189
  • Chapter 20. Fetal and Obstetric Manifestations and Infertility in the Antiphospholipid Syndrome205
  • Chapter 21. Osteo-articular Manifestations in the Antiphospholipid Syndrome213
  • Chapter 22. Ophthalmic and Otological Manifestations in the Antiphospholipid Syndrome221
  • Chapter 23. Dermatologic Manifestations in the Antiphospholipid Syndrome235
  • Chapter 24. Endocrine Manifestations in the Antiphospholipid Syndrome245
  • Chapter 25. Hematological Abnormalities in the Antiphospholipid Syndrome259
  • Chapter 26. Immunological Abnormalities in the Antiphospholipid Syndrome271
  • Chapter 27. "Primary", "Secondary", "Seronegative", "Catastrophic" and other Subsets of the Antiphos285
  • Chapter 28. Pediatric and Familial Antiphospholipid Syndrome297
  • Chapter 29. Antiphospholipid Antibodies and Malignancies317
  • Chapter 30. Antiphospholipid Antibodies and Vasculitis331
  • Chapter 31. Antiphospholipid Antibodies and Infections-Drugs343
  • Part IV: Management and Prognosis of the Antiphospholipid Syndrome (Editor: Jean-Charles Piette)359
  • Chapter 32. Management of Thrombosis in the Antiphospholipid Syndrome361
  • Chapter 33. Management of Reproductive Failure in the Antiphospholipid Syndrome375
  • Chapter 34. Management of the Difficult Aspects of the Antiphospholipid Syndrome395
  • Chapter 35. Course and Prognosis of the Antiphospholipid Syndrome409
  • Chapter 36. Novel Perspectives in the Treatment of the Antiphospholipid Syndrome–from Anticoagulat421
  • Part V: Appendix429
  • Chapter 37. The Antiphospholipid Syndrome in the Internet431
  • Chapter 38. A Patient's Guide to the Antiphospholipid Syndrome437
  • Subject Index445
Book details
  • Vendor Elsevier S & T
  • SKU 9780444509871
  • ISBN-13 9780080527307
  • Author Cervera, R.; Piette, J.C.; Shoenfeld, Yehuda
  • Category Medical
  • Subject Immunology

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This book provides the reader with a comprehensive overview of the Antiphospholipid syndrome. One of the most important advances in rheumatology and connective tissue diseases of the last decade. It provides an explanation for many previously undefined conditions with no clear pathogenesis encompassing all subspeculations in internal medicine as well as obstetrics. Clotting problems leading to strokes and myocardial infarctions (in younger people) as well as a large variety of other syndromes such as chorea, hyproadrenalism, pulmonary problems are now being understood.