Elsevier S & T

Vasopressin and Oxytocin: From Genes to Clinical Applications: From Genes to Clinical Applications

Poulain, D.; Oliet, S.; Theodosis, D.

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Table of contents
  • Cover
  • Contentsxiii
  • List of Contributorsv
  • Prefaceix
  • Acknowledgementsxi
  • Chapter 1. The magnocellular neuronal phenotype: cell-specific gene expression in the hypothalamo-ne1
  • Chapter 2. Estrogen modulates oxytocin gene expression in regions of the rat supraoptic and paravent15
  • Chapter 3. Short-term modulation of GABAA receptor function in the adult female rat31
  • Chapter 4. Cholesterol and steroid hormones: modulators of oxytocin receptor function43
  • Chapter 5. Central vasopressin systems and steroid hormones57
  • Chapter 6. Regulation of renal salt and water transporters during vasopressin escape75
  • Chapter 7. Stretch-inactivated cation channels: cellular targets for modulation of osmosensitivity i85
  • Chapter 8. Glial cells in the hypothalamo-neurohypophysial system: key elements of the regulation of95
  • Chapter 9. Functional synaptic plasticity in hypothalamic magnocellular neurons113
  • Chapter 10. Postsynaptic GABAB receptors in supraoptic oxytocin and vasopressin neurons121
  • Chapter 11. Neurohypophyseal hormones in the integration of physiological responses to immune challe127
  • Chapter 12. Involvement of the brain oxytocin system in stress coping: interactions with the hypotha147
  • Chapter 13. Expression of human vasopressin and oxytocin receptors in Escherichia coli163
  • Chapter 14. Molecular pharmacology and modeling of vasopressin receptors179
  • Chapter 15. Nonpeptide vasopressin receptor antagonists: development of selective and orally active197
  • Chapter 16. Rat vasopressin mRNA: a model system to characterize cis-acting elements and trans-actin211
  • Chapter 17. Dendritic action potentials in magnocellular neurons225
  • Chapter 18. Modulation of synaptic transmission by oxytocin and vasopressin in the supraoptic nucleu235
  • Chapter 19. The active role of dendrites in the regulation of magnocellular neurosecretory cell beha247
  • Chapter 20. Cardiovascular regulation of supraoptic vasopressin neurons257
  • Chapter 21. The central vasopressinergic system in experimental left ventricular hypertrophy and dys275
  • Chapter 22. Cardiovascular effects of oxytocin281
  • Chapter 23. Treatment of the diabetic patient: focus on cardiovascular and renal risk reduction289
  • Chapter 24. Oxytocin in parturition of guinea pigs, humans, and other species299
  • Chapter 25. Oxytocin, vasopressin and atrial natriuretic peptide control body fluid homeostasis by a309
  • Chapter 26. Positive and negative regulators of the vasopressin gene promoter in small cell lung can329
  • Chapter 27. The vasopressin receptor of corticotroph pituitary cells345
  • Chapter 28. Involvement of oxytocin and vasopressin in the pathophysiology of preterm labor and prim359
  • Subject Index367
Book details
  • Vendor Elsevier S & T
  • SKU 9780444509826
  • ISBN-13 9780080522821
  • Author Poulain, D.; Oliet, S.; Theodosis, D.
  • Category Medical
  • Subject Neuroscience

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The articles comprising this volume were first presented at the World Congress on Neurohypophysial Hormones held in Bordeaux, France on September 8-12, 2001. This conference brought together more than 170 scientists from 18 countries who belong to the different fields of interest representing research in the hypothalamo-neurohypophysial system.


Two neurohypophysial neurohormones, oxytocin and vasopressin, exert a variety of central and peripheral actions and thus involve different scientific domains, which too often, even today, do not always find the appropriate occasion to interact. This volume is composed of chapters dealing with topics varying from basic and clinical neurosciences and neuroendocrinology, to reproductive, renal, cardiovascular physiology and pathology. It encompasses all areas of current neurohypophysial research and should be of vital interest as an integrative reference volume to specialized investigators and as an excellent introductory text to students, scientists and clinicians not yet closely familiar with the field. To ensure novelty and to make sure that all topics of current importance were covered, plenary and symposium speakers as well as poster presentations concentrated on recent advances made in the last few years.